Variation in antioxidant and antimicrobial activities in Lantana camara L. flowers in relation to extraction methods

• Autorzy: Manzoor M. , Anwar F. , Sultana B. , Mushtaq M.
• Języki publikacji: EN

Abstrakty

EN

Background. The present work was designed to appraise how different extraction solvents and techniques affect the extractability of antioxidant and antimicrobial components from Lantana camara (L. camara) flowers. Material and methods. Four extraction solvents including 100% methanol, 80% methanol, 100% ethanol and 80% ethanol coupled with three extraction techniques namely stirring, microwave-assisted stirring and ultrasonic-assisted stirring employed to isolate extractable components from the flowers of L. camara. The extracts produced were evaluated for their antioxidant and antimicrobial attributes. Results and discussion. The yield of extractable components varied over a wide range 4.87-30.00% in relation to extraction solvent and techniąues. The extracts produced contained considerable amounts of total phenolics (8.28-52.34 mg GAE/100 g DW) and total flavonoids (1.24-7.88 mg CE/100 g DW). Furthermore, a promising antioxidant activity in terms of DPPHO scavenging, inhibition of linoleic acid peroxidation and reducing power, as well as antimicrobial potential of the extracts were recorded against the selected bacterial and fungal strains. Conclusions. It was concluded that both extraction solvent and techniques employed affected the antioxidant and antimicrobial attributes of the extracts from L. camara flowers. With few exceptions, overall methanolic extracts produced by ultrasonic-assisted stirring offered superior activities followed by the microwave-assisted stirring and then stirring. The results advocate the use of appropriate extraction strategies to recover potent antioxidant and antimicrobial agents from the flowers of L. camara for nutraceutical and therapeutic uses.

• Wydawca: -
• Czasopismo: Acta Scientiarum Polonorum. Technologia Alimentaria
• Rocznik: 2013
• Tom: 12
• Numer: 3
• Opis fizyczny: p.283-294,ref.

Twórcy

autor

Manzoor M.

• Department of Chemistry and Biochemistry, University of Agriculture, Faisalabad-38040, Pakistan

autor

Anwar F.

• Department of Chemistry, University of Sargodha, Sargodha-40100, Pakistan

autor

Sultana B.

• Department of Chemistry and Biochemistry, University of Agriculture, Faisalabad-38040, Pakistan

autor

Mushtaq M.

• Department of Chemistry and Biochemistry, University of Agriculture, Faisalabad-38040, Pakistan

Bibliografia

• Abou El-Kassem L.T., Mohammed R.S., El Souda S.S., El- Anssary A.A., Hawas U.W., Mohmoud K., Farrag A.R., 2012. Digalacturonide flavones from Egyptian Lantana camara flowers with in vitro antioxidant and in vivo hepatoprotective activities. Z. Naturforsch C. 67 (7-8), 381-90.
• Albayrak S., Aksoy A., Sagdic O., Hamzaoglu E., 2010. Compositions, antioxidant and antimicrobial activities of Helichrysum (Asteraceae) species collected from Turkey. Food Chem. 47 (3), 381-388.
• Anwar F., Przybylski R., 2012. Effect of solvents extraction on total phenolics and antioxidant activity of extracts from flaxseed (.Linum usitatissimum L.). Acta Sci. Pol., Technol. Aliment. 11 (3), 293-301.
• Anwar F., Kalsoom U., Sułtana B., Mushtaq M., Mehmood, T., Arshad Fl.A., 2013. Effect of drying method and extraction solvent on the total phenolics and antioxidant activity of cauliflower (Brassica oleracea L.) extracts. Int. Food Res. J. 20 (2), 653-659.
• Badakhshan M.P., Sreenivasan S., Jegathambigai R.N., Surash R., 2009. Anti-leukemia activity of methanolic extracts of Lantana camara. Phcog. Res. 1, 274-279.
• Barreira J.C.M., Ferreira I.C.F.R., O1iveira M.B.P.P., Pereira J.A., 2008. Antioxidant activities of the extracts from chestnut flower, leaf, skins and fruit. Food Chem. 107, 1106-1113.
• Begum S., Wahab A., Siddiqui B.S., Qamar F., 2000. Nematicidal constituents of the aerial parts of Lantana camara Linn. J. Nat. Prod. 63, 765-770.
• Bhakta D., Ganjewala D., 2009. Effect of leaf positions on total phenolics, flavonoids and proantho-cyanidins content and antioxidant activities in Lantana camara (L). J. Sci. Res. 1, 363-69.
• Calliste C.A., Trouillas P., Allais D.P., Duroux J.L., 2005. Castanea sativa Mili. leaves as new sources of natural antioxidant: An electronic spin resonance study. J. Agric. Food Chem. 53, 282-288.
• Calucci C.P., Zandomeneghi M., Capocchi A., Ghiringhelli S., Saviozzi F., Tozzi S., Luciano G., 2003. Effects of γ-irradiation on the free radical and antioxidant contents in nine aromatic herbs and spices. J. Agric. Food Chem. 51,927-934.
• Chaovanalikit A., Wrolstad R.E., 2004. Total anthocyanins and total phenolics of fresh and processed cherries and their antioxidant properties. J. Food Sci. 69 (1), 67-72.
• Chen H.Y., Lin Y.C., Hsieh C.L., 2007. Evaluation of antioxidant activity of aqueous extract of some selected nutraceutical herbs. Food Chem. 104, 1418-1424.
• Chun S.S., Vattem D.A., Lin Y.T., Shetty K., 2005. Phenolic antioxidants from clonal oregano (Origanum vulgare) with antimicrobial activity against Helicobacter pylon. Process Biochem. 40, 809-816.
• Day M.D., Wiley C.J., Playford J., Zalucki M.P., 2003. Lantana: Current management, status and futurę prospects. Aust. Cent. Int. Agric. Res. Canberra, 128.
• Dewanto V., Wu X., Adom K.K., Liu R.H., 2002. Thermal Processing enhances the nutritional value of tomatoes by increasing total antioxidant activity. J. Agric. Food Chem. 50, 3010-3014.
• Espin J.C., Garcia-Conesa M.T., Barberan F.A.T., 2007. Nutraceuticals: facts and fiction. Phytochem. 68,2986-3008.
• Ganjewala D., Sam S., Khan K.H., 2009. Biochemical compositions and antibacterial activities of Lantana camara plants with yellow, lavender, red and white flowers. Eur. Asia J. Biol. Sci. 3, 69-77.
• Gaweł E., 2012. Chemical composition of luceme leaf extract (EFL) and its applications as a phytobiotic in human nutrition. Acta Sci. Pol., Technol. Aliment. 11 (3), 303-310.
• Ghafoor K., Choi Y.H., Jeon J.Y., Jo I.H., 2009. Optimization of ultrasound-assisted extraction of phenolic compounds, antioxidants, and anthocyanins from grape (Vitis vinifera) seeds. J. Agric. Food Chem. 57,4988-4994.
• Ghisalberti E.L., 2000. Lantana camara L. (Verbenaceae). Fitoterapia 71 (5), 467-486.
• Gomes-de-Melo J., Sousa-de-Araujo T.A., Nobre-de-Almeida T.C.V., Lyra-de-Vasconcelos C.D., Desterro-do-Rodrigues M., Cameiro-do-Nascimento S., 2010. Antiproliferative activity, antioxidant capacity and tannin content in plants of semi-arid Brazil. Molecules 15, 8534-8542.
• Gulcin L, Oktay M., Kirecci E., Kufrevioglu O.I., 2003. Screening of antioxidant and antimicrobial activities of anise (Pimpinella anisum L.) seed extracts. Food Chem. 83, 371-382.
• Halliwell B., 1997. Antioxidants and human disease: a general introduction. Nutr. Rev. 55, 544-552.
• Hinneburg I., Dorman H.J.D., Hiltunen R., 2006. Antioxidant activities of extracts from selected culinary herbs and spices. Food Chem. 97, 122-129.
• Hsu J.L., Su C.Y., Lin J.W., 2006. Resection of a granular celi tumor of the larynx followed by medialization laryngoplasty with bipedicled stemohyoid muscle transpo- sition. Otolaryngol. 135 (6), 983-985.
• Hussain A.I., Anwar F., Sherazi S.T.H., Przybylski R., 2008. Chemical composition, antioxidant and antimicrobial activities of basil (Ocimum basilicum) essential oils depends on seasonal variations. Food Chem. 108 (3), 986-995.
• Iqbal S., Bhanger M.I., 2007. Stabilization of sunflower oil by garlic extracts during accelerated storage. Food Chem. 100(1), 246-254.
• Iqbal S., Bhanger M.I., Anwar F., 2007. Antioxidant properties and components of some commercially available varieties of rice bran in Pakistan. Food Chem. 93,340-361.
• Jing W., Baoguo S., Yanping C., Yuan T., Xuehong L., 2008. Optimization of ultrasound-assisted extraction of phenolic compounds from wheat bran. Food Chem. 106, 804-810.
• Kalita S., Kumar G., Karthik L., Rao K.V.B., 2011. Phytochemical composition and in-vitro hemolytic activity of Lantana camara L. (Yerbenaceae) leaves. Pharmacol. Newsletter 1, 59-67.
• Kaur S., Kumar S., Kaur P., Chandel M., 2010. Study of antimutagenic potential of phytoconstituents isolated from Terminalia arjuna in the SalmonellafMicrosome Assay. Am. J. Biomed. Sci. 2, 164-77.
• Khan M.K., Vian M.A., Tixier A.S.F., Dangles O., Chemat F., 2010. Ultrasound-assisted extraction of polyphenols (flavanone glycosides) from orange peel (Citrus sinensis L.). Food Chem. 119, 851-858.
• Kim N.Y., Song E.J., Kwon D.Y., Kim H.P., Heo M.Y., 2008. Antioxidant and antigenotoxic activities of Korean fermented soybean. Food Chem. Toxicol. 46 (3), 1184-1189.
• Kumar M.S., Maneemegalai S., 2008. Evaluation of larvicidal effect of Lantana camara Linn against mosquito species Aedes aegypti and Culex quinquefasciatus. Ad- van. Biol. Res. 2, 39-43.
• Lifschitz C., 2012. New actions for old nutrients. Acta Sci. Pol., Technol. Aliment. 11 (2), 183-192.
• Mariod A.A., Abdelwahab S.I., Elkheir S., Ahmed J.M., Fauzi P.N.M., Chuen Ch.S., 2012. Antioxidant activity of different parts from Annona squamosa, and Catunaregam nilotica methanolic extract. Acta Sci. Pol., Technol. Aliment. 11 (3), 249-257.
• National Committee for Clinical Laboratory Standards (NCCLS). Approved Standard M2-A6. 1997. NCCLS Wayne, PA.
• National Committee for Clinical Laboratory Standards (NCCLS). M100-S9. 1999. NCCLS Wayne, PA.
• Nepote V., Grosso N.R., Guzman C.A., 2002. Extraction of antioxidant components from peanut skins. Grassay Aceites 53 (4), 391-395.
• Novak I., Janeiro P., Seruga M., Brett A.M.O., 2008. Ultrasound extracted flavonoids from four varieties of Portuguese red grape skins determined by reverse-phase high-performance liquid chromatography with electrochemical detection. Anal. Chim. Acta 630, 107-115.
• Olaleye M.T., Akinmoladun A.C., Ogunboye A.A., Akindahunsi A.A., 2010. Antioxidant activity and hepatoprotective property of leaf extracts of Boerhaavia diffusa Linn against acetaminophen-induced liver damage in rats. Food Chem. Toxicol. 99 (3), 450-454.
• Patel J., Kumar G.S., Deviprasad S.P., Deepika S., Qureshi M.S., 2011. Phytochemical and anthelmintic evaluation of Lantana camara (L.) var. aculeate leaves against Pheretima posthuma. J. Global Trends Pharm. Sci. 2, 11-20.
• Raghu C., Ashok G., Dhanaraj S., Suresh B., Vijayan P., 2004. In vitro cytotoxic activity of Lantana camara Linn. Ind. J. Pharmacol. 104 (3), 1106-1114.
• Ribeiro B., Rangel J., Valentao P., Andrade P.B., Pereira J.A., Bolke H., 2007. Organie acids in two Portuguese chestnut (Castanea sativa Miller) varieties. Food Chem. 100, 504-508.
• Samy R.P., Ignacimuthu S., 2000. Antibacterial activity of some folklore medicinal plants used by tribals in Western Ghats of India. J. Ethnopharm. 69, 63-71.
• Sing C., Zerba K., Nelson M., Lussier-Cacan S., Kardia S., 2000. The relative role of invariant and context dependent genetic effects in predicting cardiovascular disease. Atherosclerosis 151 (1), 235.
• Suhaj M., 2006. Spice antioxidants isolation and their antiradical activity: a review. J. Food Compos. Anal. 19, 531-537.
• Sun Y., Liu D., Chen J., Ye X., Yu D., 2011. Effects of different factors of ultrasound treatment on the extraction yield of the all-trans-b-carotene from citrus peels. Ultra- son Sonochem. 18, 243-249.
• Shabir G., Anwar F., Sułtana B., Khalid Z.M., Afzal M., Khan Q.M., Ashrafuzzaman M., 2011. Antioxidant and antimicrobial attributes and phenolics of different solvent extracts from leaves, flowers and bark of Gold Mohar [,DeIonix regia (Bojer ex Hook.) Raf.]. Molecules 16, 7302-7319.
• Sultana B., Anwar F., Ashraf M., 2009. Effect of extraction solvent/technique on the antioxidant activity of selected medicinal plant extracts. Molecules 14, 2167-2180.
• Tadhani M.B., Patel V.FL, Subhash R., 2007. In-vitro antioxidant activities of Stevia rebaudiana leaves and callus. J. Food Compos. Anal. 20, 323-329.
• Tepe B., Sokmen M., Akpulat H.A., Sokmen A., 2006. Screening of the antioxidant potentials of six Salvia species from Turkey. Food Chem. 95, 200-204.
• Thamotharan G., Sekar G., Ganesh T., Sen S., Chakraborty R., Kumar S.N., 2010. Antiulcerogenic effects ot Lantana camara Linn. leaves On in-vivo test models in rats. Asian J. Pharm. Clinic. Res. 3, 57-60.
• Toma M., Vinatoru M., Paniwnyk L., Mason T.J., 2001. Ultrason Sonochem. 8, 137.
• Tsai T.H., Tsai T.H., Chien Y.C., Lee C.W., Tsai P.J., 2008. In vitro antimicrobial activities against cariogenic streptococci and their antioxidant capacities: A comparative study of green tea versus different herbs. Food Chem. 110, 859-864.
• Valentao P, Femandes E., Carvalho F., Andrade P.B., Seabra R.M., Bastos M.L., 2002. Antioxidative properties of cardoon (Cynara cardunculus L.) infuzion against superoxide radical, hydroxyl radical and hypochlorous acid. J. Agric. Food Chem. 50, 4989-4993.
• Voravuthikunchai S.P, Kitpipit L., 2005. Activity of medicinal plant extracts against hospital isolates of methicillinresistant Staphylococcus aureus. Clin. Microbiol. Infec. 11,510-512.
• Wang L., Weller C.L., 2006. Recent advances in extraction of nutraceuticals from plants. Trends Food Sci. Technol. 17,300-312.
• Wojdyło A., Oszmiański J.O., Czemerys R., 2007. Antioxidant activity and phenolic compoimds in 32 selected herbs. Food Chem. 105, 940-949.
• Wolfe A.R., Ogbonna E.M., Lim S., Li Y., Zhang J., 2009. Dietary linoleic and oleic fatty acids in relation to severe depressed mood: 10 years follow-up of a national co- hort. Prog. Neuro-Psychoph. 33 (6), 972-977.
• Yen G.C., Duh P.D., Chuang D.Y., 2007. Antioxidant activity of anthraquinones and anthrone. Food Chem. 70, 307-315.
• Zhang G., He L., Hu M., 2011. Optimized ultrasonic-assisted extraction of flavonoids from Prunella vulgaris L. and evaluation of antioxidant activities in-vitro. Innov. Food Sci. Emer. Techn. 12,18-25.
• Zhang Y., Li X., Wang Z., 2010. Antioxidant activities of leaf extract of Salvia miltiorrhiza Bunge and related phenolic constituents. Food Chem. Toxicol. 54,607-616.
• Zia-ur-Rehman, Salariya A.M., Habib F., 2003. Antioxidant activity of ginger extract in sunflower oil. J. Sci. Food Agric. 83, 624-629.

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