EN
Presenting detailed picture of psychical problems in healthy controls and patients enabled to see indirect important effect of polyetiological determinants of metabolism of minerals in 388 subjects included in the study, whose blood serum and hair were tested for the content of magnesium, potassium, sodium, calcium, phosphorus, chlorine, zinc, copper, iron, lithium and lead. The most important factor is nutrition. The subjects, except 79 healthy controls, were fed in residential accomodation, so they received almost the same meals in their institution. Psychiatric patients and mentally handicapped received drugs from the same group - psychotropic drugs, they stayed in the same accomodation and microclimate, their lifestyle was also similar (little exercise, little fresh air) and therefore they had a limited oportunity to obtain vital elements from surrounding environment. They were not much exposed to heavy metals in their environment, so the content of lead is much lower than in the studies by other authors from more industrialized areas. In the mentally handicapped, decreased contents of magnesium and calcium were found in serum and hair, the content of copper was lower than in the controls, but the content of iron was higher. The content of potassium in serum and hair in psychiatric patients was the highest of all subjects, which may be important for diagnosis.