Helicobacter sp. microorganisms do not alter proliferative activity of gastric epithelial cells in naturally infected swine

• Autorzy: Sapierzynski R. , Fabisiak M. , Kizerwetter-Swida M. , Dolka I.
• Języki publikacji: EN

Abstrakty

EN

In the presented study, an evaluation of influence of different Helicobacter species and gastritis on intensity of cellular proliferation in pyloric glands of pigs' stomach was performed. Samples of gastric antral mucosa obtained from 38 slaughtered pigs with known Helicobacter sp. and gastric inflammation statuses were stained with haematoxylin-eosin and immunohistochemically, for Ki67 antigen expression. Proliferative activity of epithelial cells was assessed by determination of: a ratio of proliferative zone length to gastric crypts length, an average percentage of cells showing Ki67 expression in proliferative zones of antral glands, and value of mitotic index in glands' proliferative zones. None of the comparisons revealed statistically significant differences between animal groups with or without gastric inflammation, as well as between groups with or without Helicobacter colonisation. Additionally, no statistically significant differences were found between the group of animals that were infected with Candidatus Helicobacter suis, and that with the stomach colonised by different species of Helicobacter microorganisms.

Słowa kluczowe

EN

gastrointestinal tract; Helicobacter; animal infection; epithelial cell; gastritis; immunohistochemistry; microorganism; pig; proliferation; stomach; gastric mucosa

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2011
• Tom: 55
• Numer: 1
• Opis fizyczny: p.9-14,fig.,ref.

Twórcy

autor

Sapierzynski R.

• Department of Pathology and Veterinary Diagnostics, Faculty of Veterinary Medicine, Warsaw University of Life Sciences (SGGW), 02–776 Warsaw, Poland

autor

Fabisiak M.

autor

Kizerwetter-Swida M.

autor

Dolka I.

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