Design, molecular docking, drug-likeness, and molecular dynamics studies of 1,2,4-trioxane derivatives as novel Plasmodium falciparum falcipain-2 (FP-2) inhibitors

• Autorzy: Ghosh S. , Chetia D. , Gogoi N. , Rudrapal M.
• Języki publikacji: EN

Abstrakty

EN

Słowa kluczowe

EN

molecular docking; molecular dynamics; 1,2,4-trioxane; Plasmodium falciparum; drug resistance; artemisinin; combination therapy

• Wydawca: -
• Czasopismo: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
• Rocznik: 2021
• Tom: 102
• Numer: 3
• Opis fizyczny: p.257-275,fig.,ref.

Twórcy

autor

Ghosh S.

• Deptartment of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, Assam, India

autor

Chetia D.

• Deptartment of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, Assam, India

autor

Gogoi N.

• Deptartment of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, Assam, India

autor

Rudrapal M.

• Department of Pharmaceutical Chemistry, Rasiklal M. Dhariwal Institute of Pharmaceutical Education and Research, Chinchwad, Pune, Maharashtra, India

Identyfikatory

DOI

10.5114/bta.2021.108722