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2014 | 74 | 3 |

Tytuł artykułu

Theta oscillations in the posterior hypothalamic area-in vivo approach

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Numerous studies showed that occurrence of hippocampal theta rhythm is critically dependent on the integrity of a number structures localized at the level of brainstem and diencephalon. In detailed electrophysiological studies, conducted on anesthetized rats, we demonstrated that the posterior hypothalamic area (PHa), is not only a modulator of hippocampal formation theta but also could generate theta activity independently. The most effective areas in generation of examined EEG pattern were the supramammillary and posterior hypothalamic nuclei. Pharmacological manipulation reviled that PHa theta activity had a cholinergic (muscarinic) profile. Local injection of orexin A and B never induced theta activity in PHa. Finally, we showed that mineralocorticoid receptor but not gap junction play crucial role in generation of the posterior hypothalamic theta rhythm. Studies supported by NCN grant no. 2011/01/B/NZ4/00373.

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Wydawca

-

Rocznik

Tom

74

Numer

3

Opis fizyczny

p.331

Twórcy

autor
  • Department of Neurobiology, University of Lodz, Lodz, Poland
  • Department of Neurobiology, University of Lodz, Lodz, Poland
autor
  • Department of Neurobiology, University of Lodz, Lodz, Poland
autor
  • Department of Neurobiology, University of Lodz, Lodz, Poland
  • Department of Neurobiology, University of Lodz, Lodz, Poland
autor
  • Department of Neurobiology, University of Lodz, Lodz, Poland

Bibliografia

Typ dokumentu

Bibliografia

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