PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2019 | 23 |

Tytuł artykułu

Characterization of catechins from Smilax domingensis Willd. in Cuba

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Gas Chromatography coupled with mass spectrometry was applied to study the fragmentation of selected flavonoids from the ethanolic extract of Smilax domingensis Willd., Smilacaceae, known as zarzaparrilla, after Soxhlet extraction during 20 hours. Compounds belonging to one of the major subgroups found in common plants, i.e. flavanols were studied. Following solvent extraction and derivatization using BSTFA, possibly two different metabolites from the same chemical group were characterized in one analytical run: (+)-catechin and (-)-epicatechin. For the very first time, qualitative data on these analytes in the drug were determined after detailed validation of a sensitive, cheap and reliable GC-MS method.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

23

Opis fizyczny

p.297-305,fig.,ref.

Twórcy

  • Faculty of Chemical Sciences, Guayaquil University, Guayaquil , Ecuador
autor
  • Department of Pharmacy, Faculty of Pharmacy and Foods, Havana University, Havana, Cuba
autor
  • Department of Pharmacy, Faculty of Pharmacy and Foods, Havana University, Havana, Cuba
autor
  • National Center of Toxicology (CENATOX), Military Hospital "Carlos J. Finlay", Havana, Cuba
autor
  • ARVARNAM, 16 lot. les Rosiers, Quartier Thoraille, 97215, Riviere-Salee, Martinica

Bibliografia

  • [1] Cáceres, A., Cruz, S. M., Martínez, V., Gaitán, I., Santizo, A., Gattuso, S. and Gattuso, M. (2012). Ethnobotanical, Pharmacognostical, Pharmacological and Phytochemical Studies on Smilax domingensis in Guatemala. Revista Brasileira de Farmacognosia, 22, 239-248. https://doi.org/10.1590/S0102-695X2011005000211
  • [2] Bérdy, J., Aszalo, A., Bostian, M. and McKnitt, K.L. (1982). CRC Handbook of Antibiotic Compounds. Vol. 7, Part 2, Boca Ratón, CRC Press, 255.
  • [3] Kiprop, A. K., Pourtier, E. and Kimutai, S. K. GC-MS and ESI-MS detection of catechol. International Journal of Education and Research, Vol. 1 No. 12 December 2013, pp. 1-12.
  • [4] Kumari, S.; Stevens, D.; Kind, T.; Denkert, C.; Fiehn, O. (2011). Applying in-silico retention index and mass spectra matching for identification of unknown metabolites in accurate mass GC-TOF mass spectrometry. Anal. Chem. 83, 5895-5902
  • [5] Little, J. L. (1999). Artifacts in trimethylsilyl derivatization reactions and ways to avoid them. J. Chromatogr. A 844, 1-22
  • [6] Menikarachchi, L.C.; Hill, D.W.; Hamdalla, M.A.; Mandoiu, II; Grant, D.F. (2013). In silico enzymatic synthesis of a 400,000 compound biochemical database for nontargeted metabolomics. J. Chem. Inf. Model. 53, 2483-2492
  • [7] Roig, J. T. (2014). Plantas medicinales, aromáticas o venenosas de Cuba. Editorial Científico Técnica, La Habana, Cuba, 618-619.
  • [8] Rohloff J. (2015). Analysis of Phenolic and Cyclic Compounds in Plants Using Derivatization Techniques in Combination with GC-MS-Based Metabolite Profiling. Molecules, 20, 3431-3462; doi:10.3390/molecules20023431
  • [9] Sarria-Villa R. A, Gallo-Corredor J. A, Páez M. A. (2017). Isolation of Catechin and Gallic Acid from Colombian Bark of Pinus patula. Chemical Sciences Journal, Volume 8, Issue 4, 1000174. doi: 10.4172/2150-3494.1000174
  • [10] Stevens WD, Ulloa-Ulloa C, Pool A, Montiel OM. (2001). Flora de Nicaragua. Monographs in Systematic Botany 85(3). Missouri Botanical Garden, St. Louis, p. 1911-2666
  • [11] Tsimogiannis D., Samiotaki M., Panayotou G and Oreopoulou V. (2007). Characterization of Flavonoid Subgroups and Hydroxy Substitution by HPLC-MS/MS. Molecules, 12, 593-606
  • [12] Yaque, J.G., Monan, M., Cuéllar, A., de Armas, T., Gómez, E. and Dopico, E. (2017) Pharmacognostic and Phytochemical Studies of Smilax domingensis Willd. in Cuba. American Journal of Plant Sciences, 8, 1462-1470. https://doi.org/10.4236/ajps.2017.86100
  • [13] Zhang, Y.; Zhang, P. & Cheng, Y. (2008). Structural characterization of isoprenylated flavonoids from Kushen by electrospray ionization multistage tandem mass spectrometry. Journal of Mass Spectrometry, 43, 10, 1421-1431
  • [14] Zhang K. and Zuo Y. (2004). GC-MS Determination of Flavonoids and Phenolic and Benzoic Acids in Human Plasma after Consumption of Cranberry Juice. J. Agric. Food Chem. 52, 222-227

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-daba89be-6fcf-4964-a778-69fa5436a419
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.