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2019 | 65 | 4 |

Tytuł artykułu

Cerebral malaria and multi-organ dysfunction in an adult woman with Plasmodium falciparum infection imported from Cameroon: a case report

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Malaria is one of the most life-threatening parasitic diseases caused by the protozoa of the genus Plasmodium, occurring in the tropical and subtropical regions. Misdiagnosed infection can progress to a wide range of life-threatening pathologies, including severe anemia and cerebral malaria which can lead to death even few days after first symptoms appearance. Cerebral malaria is rare in adults and most cases are connected to children under 5 years old living in malaria endemic areas. In this article we describe cerebral malaria caused by the Plasmodium falciparum in a 45-year-old Polish patient, who traveled to Cameroon without any malaria prophylaxis. The patient had been treated in an intensive care unit because of multi-organ dysfunction as a result of the delayed malaria diagnosis. The presence of thrombocytopenia, anemia, metabolic acidosis, acute respiratory distress syndrome and multi-organ dysfunction involving liver, kidneys, and brain created an image of advanced severe malaria. Loss of consciousness, GCS 6, and the presence of asexual Plasmodium falciparum forms in blood films are the evidence of cerebral malaria. To avoid development of cerebral malaria, the illness should be diagnosed immediately. The cerebral malaria can occur also in adult healthy individuals. Appropriate treatment with intravenous artemisine can protect the patient from lifethreatening complications. Prolonged anemia after treatment can be a consequence of artemisine usage as well as a severe malaria sequel.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

65

Numer

4

Opis fizyczny

p.427–431,fig.,ref.

Twórcy

autor
  • Department of Tropical and Parasitic Diseases, Poznan University of Medical Sciences, Poznań, Poland
  • Central Laboratory of Microbiology, H. Święcicki University Hospital, Poznań, Poland
autor
  • Intensive Care Unit, J. Struś Multidiscipline City Hospital, Poznań, Poland
autor
  • Department of Tropical and Parasitic Diseases, Poznan University of Medical Sciences, Poznań, Poland

Bibliografia

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  • [3] Wassmer S.K., Taylor T.E., Rathod Ph., Mishra S.K., Mohaty S., Arevalo-Herrera M., Duraisingh M.T., Smith J.D. 2015. Investigating the pathogenesis of severe malaria: a multidisciplinary and crossgeographical approach. Journal of Tropical Medicine and Hygiene 9 (Suppl): 42-56. doi:10.4269/ajtmh.14-0841
  • [4] White N.J. 2018. Anemia and malaria. Malaria Journal 17: 371. doi:10.1186/s12936-018-2509-9
  • [5] Taneja S., Agavri N. 2019. Autoimmune haemolytic anaemia associated with P. vivax malaria. Tropical Doctor 49: 54-55. doi:10.1177/0049475518804381
  • [6] Takaya S., Kato Y., Katanami Y., Yamamoto K., Kutsuna S., Takeshita N., Hayakawa K., Kanagawa S., Komaki-Yasuda K., Kano S., Ohmagari N. 2019. Imported malaria at a referral hospital In Tokyo from 2005 to 2016 – clinical experience and challenges in a non-endemic setting. 2019. American Journal of Tropical Medicine and Hygiene 100: 828-834. doi:10.4269/ajtm
  • [7] Ashley E.A., Pyae Phyo A., Woodrow C.J. 2018. Malaria. Lancet 391(10130): 1608-1621. doi:10.1016/S0140-6736(18)30324-6
  • [8] Ishag A., Yassin I., Gesin I. 2018. Efficacy and safety of artemisin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Sudan: a systematic review and meta-analysis. Malaria Journal 17: 110. doi:10.1186/s12936-018-2265-x
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  • [11] Brown D.D., Solomon S., Lerner D., Del Rio M. 2019. Malaria and acute kidney injury. Pediatric Nephrology 31. doi:10.1007/s00467-018-4191-0
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  • [14] Dayanand K.K., Kishore P., Chandrashekar V., Achur R.N., Ghosh S.K., Kakkilaya S.B. et al. 2019. Malaria severity in Mangdum City in the Southwestern Coastal Region of India. American Journal of Tropical Medicine and Hygiene 100: 275-279. doi:10.4269/ajtmh.18-0005
  • [15] Naing C., Whittaker M.A. 2018. Severe thrombocytopenia in patients with vivax malaria compared to falciparum malaria: a systemic review and metaanalysis. Infectious Diseases of Poverty 7: 10. doi:10.1186/s40249-018-0392-9
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  • [18] D’Abramo A., Gebremeskal Tekle S., Jannetta M., Scorzolini L., Oliva A., Paglia M.G. 2018. Severe Plasmodium ovale malaria complicated by acute respiratory distress syndrome in a young Caucasian man. 2018. Malaria Journal 17: 139. doi:10.1186/s12936-018-2289-2
  • [19] Shan P.J., Koshy J., Everett N., Attia E. 2018. Severe Plasmodium falciparum malaria treated with investigational artesunate in the United States. Journal of Pharmacy Practice 897190018782367. doi:10.1177/0897190018782367
  • [20] Salehi M., Masoumi-Asl H., Assarian M., Khoshnam-Red N., Haghi A.M., Nikbakht M., Khalili H. 2019. Delayed hemolytic anemia after treatment with artesunate: case report and literature review. Current Drug Safety 14: 60-66. doi:10.2174/1574886313666181109150157
  • [21] Hasegawe C., Kudo M., Mamyame H., Kimura M. 2018. Severe delayed haemolytic anaemia associated with artemether-lumefantrine treatment of malaria in a Japanese traveler. Journal of Infection and Chemotherapy 24: 216-219. doi:10.1016/j.jiac.2017.10.008

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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