Siponimod (Mayzent) downregulates RhoA and cell surface expression of the S1P1 and CX3CR1 receptors in mouse RAW 264.7 macrophages

• Autorzy: Uosef A. , Vaughn N. , Chu X. , Elshawwaf M. , Abelelshafy A.A.A. , Elsaid K.M.K. , Ghobrial R.M. , Kloc M.
• Języki publikacji: EN

Abstrakty

EN

Słowa kluczowe

EN

multiple sclerosis; treatment; therapeutic effect; fingolimod; siponimod; inhibitory effect; sphingosine 1-phosphate; chemokine; CX3CR1 receptor; macrophage; RhoA protein

• Wydawca: -
• Czasopismo: Archivum Immunologiae et Therapiae Experimentalis
• Rocznik: 2020
• Tom: 68
• Numer: 3
• Opis fizyczny: Article 19 [8p.], fig.,ref.

Twórcy

autor

Uosef A.

• The Houston Methodist Research Institute, Houston, TX, USA
• Department of Surgery, Houston Methodist Hospital, 6550 Fannin St., Houston, TX, 77030, USA

autor

Vaughn N.

• The Houston Methodist Research Institute, Houston, TX, USA

autor

Chu X.

• The Houston Methodist Research Institute, Houston, TX, USA

autor

Elshawwaf M.

• The Houston Methodist Research Institute, Houston, TX, USA
• Department of Surgery, Houston Methodist Hospital, 6550 Fannin St., Houston, TX, 77030, USA

autor

Abelelshafy A.A.A.

• The Houston Methodist Research Institute, Houston, TX, USA
• Department of Surgery, Houston Methodist Hospital, 6550 Fannin St., Houston, TX, 77030, USA
• Department of General Surgery, Faculty of Medicine, Ain-Shams University, Cairo, Egypt

autor

Elsaid K.M.K.

• The Houston Methodist Research Institute, Houston, TX, USA
• Department of Surgery, Houston Methodist Hospital, 6550 Fannin St., Houston, TX, 77030, USA
• Department of General Surgery, Faculty of Medicine, Ain-Shams University, Cairo, Egypt

autor

Ghobrial R.M.

• The Houston Methodist Research Institute, Houston, TX, USA
• Department of Surgery, Houston Methodist Hospital, 6550 Fannin St., Houston, TX, 77030, USA

autor

Kloc M.

• The Houston Methodist Research Institute, Houston, TX, USA
• Department of Surgery, Houston Methodist Hospital, 6550 Fannin St., Houston, TX, 77030, USA
• Department of Genetics, The University of Texas, M.D. Anderson Cancer Center, Houston, TX, USA

Identyfikatory

DOI

10.1007/s00005-020-00584-4