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2013 | 16 | 1 |

Tytuł artykułu

Autophagy in physiological and pathological processes - selected aspects

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Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
This paper describes a model of cell death, called autophagy, one among other typical and atypical processes of cell death. This phenomenon is present in the organism, from conception until death, and is conditioned by many genes of ATG family, or mTOR kinase and specific proteins, like BNIP3. This process plays a very important role not only in physiological functions of the organism but also in pathological, such as Alzheimer or Huntington disease, as well as diseases caused by viruses.

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-

Rocznik

Tom

16

Numer

1

Opis fizyczny

p.173-180,fig.,ref.

Twórcy

  • Department of Immunology, Faculty of Biology, University of Szczecin, Felczaka 3c, 71-412 Szczecin, Poland
  • Department of Immunology, Faculty of Biology, University of Szczecin, Felczaka 3c, 71-412 Szczecin, Poland
autor
  • Department of Microbiology, Faculty of Biology, University of Szczecin, Felczaka 3c, 71-412 Szczecin, Poland

Bibliografia

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  • Fabri M, Realegeno SE, Jo EK, Modlin RL (2011) Role of autophagy in the host response to microbial infection and potential for therapy. Curr Opin Immunol 23: 65-70.
  • Gade P (2011) IFN-autophagy and tumor supression: a novel IFN-γ induced signaling cascade involving Activated transcriptor factor-6 (ATF-6) that collaborates with C/EBP-beta and promotes tumor suppression. Cytokine 56: 60-61.
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  • Harris J (2011) Autophagy and cytokines. Cytokine 56: 140-144.
  • Hippert MM, O’Toole PS, Thorburn A (2006) Autophagy in cancer: good, bad or both? Cancer Res 66: 9349-9351.
  • Hubbard VM, Valdor R, Patel B, Singh R, Cuervo AM, Macian F (2010) Macroautophagy regulates energy metabolism during effector T cell activation. J Immunol 185: 7349-7357.
  • Lamparska-Przybysz M, Motyl T (2005) Autophagy – the tool of cancer cell survival or death? Postępy Biologii Komórki 32: 13-22.
  • Lee HK, Iwasaki A (2008) Autophagy and antiviral immunity. Curr Opin Immunol 20: 23-29.
  • Levine B, Kroemer G (2008) Autophagy in the pathogenesis of disease. Cell 132: 27-42.
  • Levine B, Mizushima N, Virgin HW (2011) Autophagy in immunity and inflammation. Nature 469: 323-335.
  • Marino G, López-Otın C (2004) Autophagy: molecular mechanisms, physiological functions and relevance in human pathology. Cell Mol Life Sci 61: 1439-1454.
  • Maruniewicz M, Wojtaszek P (2007) The origin and evolution of cell death. Postępy Biologii Komórki 34: 651-777.
  • Matryniszyn L, Orłowski P, Krzyżowska M, Niemiałtowski MG (2008) Autophagy in viral and bacterial infections: molecular roulette. Postępy Biologii Komórki 35: 351-368
  • Meijer AJ, Codogno P (2006) Signalling and autophagy regulation in health, aging and disease. Mol Aspects Med 27: 411-425.
  • Morris S, Swanson MS, Liebermann A, Reed M, Yue Z, Lindell DM, Lukacs NW (2011) Autophagy-mediated dendritic cell activation is essential for innate cytokine production and APC function with respiratory syncytial virus responses. J Immunol 187: 3953-3961.
  • Nascimbeni AC, Fanin M, Masiero E, Angelini C, Sandri M (2012) The role of autophagy in the pathogenesis of glycogen storage disease type II (GSDII). Cell Death Differ 19: 1698-1708.
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  • Randow F, Munz C (2012) Autophagy in the regulation of pathogen replication and adaptive immunity. Trends Immunol 33: 475-487.
  • Remijsen Q, Kuijpers TW, Wirawan E, Lippens S, Vandenabeele P, Berghe TV (2011) Dying for a causa: NETosis, mechanisms behind an antimicrobial cell death sodality. Cell Death Differ 18: 581-588.
  • Rudnicka KW, Szczęsna E, Miszczyk E, Mikołajczyk--Chmiela M (2011) Apoptosis and autophagy – mechanisms and detection methods. Postępy Biologii Komórki 38: 247-265.
  • Shaw MH, Kamada N, Warner N, Kim YG, Nunez G (2011) The ever-expanding function of NOD2: autophagy, viral recognition, and T cell activation. Trends Immunol 32: 73-79.
  • Sobolewska A, Gajewska M, Motyl T (2010) Role of autophagy in the mammogenesis of bovine mammary glands on the model of mammospheres. Med Weter 66: 222-227.
  • Sobolewska A, Gajewska M, Zarzyńska J, Gajkowska B, Motyl T (2009) IGF-I, EGF, and sex steroids regulate autophagy in bovine mammary epithelial cells via the mTOR pathway. Eur J Cell Biol 88: 117-130.
  • Stępień A, Izdebska M, Grzanka A (2007) The types of cell death. Postępy Higieny Medycyny Doświadczalnej 61: 420-428.
  • Swoboda E, Strządała L (2009) BNIP3 as an atypical representative of the Bcl-2 protein family. Part 1: BNIP3, a regulator of non-apoptotic programmed cell death. Postępy Higieny Medycyny Doświadczalnej 63: 409-417.
  • Uchiyama Y, Shibata M, Koike M, Yoshimura K, Sasaki M (2008) Autophagy – physiology and pathophysiology. Histochem Cell Biol 129: 407-420.
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  • Wiwaran E, Vanden Berghe T, Lippens S, Agostinis P, Vandenabeele P (2012) Autophagy: for better or for worse. Cell Res 22: 43-61.

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