PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
1988 | 39 | 2 |

Tytuł artykułu

Effect of cold exposure on the concentration of triglyceride in the liver of the rat

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Górski, J., Górska, M. and Hryniewicz, A.: Effect of cold exposure on the concentration of triglyceride in the liver of the rat. Acta physiol, pol., 1980, 39 (2): 136-142. The aim of the present study was to examine an effect of cold exposure on the concentration of triglycerides (TG) in the rat's liver. The rats were divided into the following groups: control, fed with oil, treated with hydrocortisone, fed with oil and treated with hydrocortisone, treated with noradrenaline. The rats exposed to cold were kept in wire cages (one rat in one cage) in the cold room at temperature +2°C. They had free access to food (pellet diet for rodents) and water. In the control group the exposure to cold increased mildly (though significantly) the TG concentration after 1 and 3 h and had no effect after 2 and 24 h. It did not affect the concentration of plasma free fatty acids (FFA). At room temperature feeding with oil (2 ml/100 g of body weight) alone, and combined with hydrocortisone treatment (5 mg/100 g of body weight) as well as treatment with noradrenaline (0.1 mg/100 g of body weight) had no effect on the liver TG concentration, although the concentration of plasma FFA was increased. Exposure to cold for 3 h increased markedly the liver TG concentration in each of those groups. It is concluded that exposure to cold elicits a mechanism, which in the presence of elevated plasma FFA concentration induces accumulation of TG in the liver.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

39

Numer

2

Opis fizyczny

p.136-142,ref.

Twórcy

autor
  • Department of Physiology and Endocrinology, School of Medicine, Bialystok, Poland
autor
  • Department of Physiology and Endocrinology, School of Medicine, Bialystok, Poland
  • Department of Physiology and Endocrinology, School of Medicine, Bialystok, Poland

Bibliografia

  • 1. Beynen, A. C., Van der Molen, A. J., Geelen, M. J. H. (1981) Control of lipolysis in isolated hepatocytes by insulin and glucagon. Harm. Metab. Res. 13. 183-184.
  • 2. Beynen, A. C. (1982) Short-term regulation of hepatic carbohydrate and lipid metabolism by insulin and glucagon. Endokrinologie 80. 238-252.
  • 3. Brindley, D. W. (1981) Regulation of hepatic triacyglycerol synthesis and lipoprotein metabolism by glucocorticoids. Clin. Sci. 61. 129-133.
  • 4. Brodie, B. B., Butler, W. M., Jr., Horning, M. C., MaiCkel, R. P., Maling, H. M. (1961) Alcohol-induced triglyceride deposition in liver through derangement of fat transport. Amer. J. Clin. Nutr. 9. 432-435.
  • 5. Brodie, B. B., Maickel, R. P. (1963) Role of the sympathetic nervous system in drug-induced fatty liver. Ann. N.Y. Acad. Sci. 104. 1049-1058.
  • 6. Carlson, L. A. (1963) Determination of serum triglycerides. J. Atheroscler. Res. 3. 334-336.
  • 7. Carlson, L. A., Fröberg, S. O., Nye, E. R. (1966) Acute effect of nicotinic acid on plasma, liver, heart and muscle lipids. Nicotinic acid in the rat. II. Acta Med. Scand. 180. 571-579.
  • 8. Debeer, L. J., Beynen, A. C., Mannearts, G. P., Geelen, M. J. H. (1982) Lipolysis of hepatic triacylglycerol stores. FEBS Letters 140. 159-164.
  • 9. DiLuzio, N. R. (1958) Effect of acute alcohol intoxication on liver and plasma lipid fractions of the rat. Amer. J. Physiol. 194. 453-456.
  • 10. Doi, K., Ohno, T., Kuroshima, A. (1982) Role of endocrine pancreas in temperature acclimation. Life Sci. 30. 2253-2259.
  • 11. Duncombe, W. G. (1964) The colorimetric micro-determination of nonesterified fatty acids in plasma. Clin. Chim. Acta 9. 122-125.
  • 12. Fröberg, S. O. (1971) Effect of acute exercise on tissue lipids in rats. Metabolism 20. 714-720.
  • 13. Fukuda, N., Hori, K., Sugano, M. (1976) Effects of exercise on plasma and liver lipids of rats. Part I. Effects of the lapse of time after exercise and of the intensities of exercise on lipids of rats. J. Agric. Chem. Soc. Japan 50. 17-22.
  • 14. Galletti, F. (1967) An improved colorimetric micromethod for the determination of serum glycerides. Clin. Chim. Acta 15. 184-186.
  • 15. Górski, J. (1983) Energy sources mobilization during muscular exercise in pregnant rats. Acta Physiol. Pol. 34. 269-276.
  • 16. Górski, J. (1982) Effect of exercise on metabolism of energy substrates in pregnant mother and her fetus in the rat. In: Biochemistry oi Exercise, Eds: H. G. Knuttgen, J. A. Vogel and J. Poortmans, pp. 229-233, Human Kinetic Publishers, Inc. Champaign, II 61820.
  • 17. Górski, J., Kuryliszyn, A., Wereszczyńska, U. (1981) Effect of acute cold exposure on the mobilization of intramuscular glycogen and triglycerides in the rat. Acta Physiol. Pol. 32. 755-759.
  • 18. Górski, J., Kiryluk, T. (1980) The post-exercise recovery of triglycerides in rat tissues. Eur. J. Appl. Physiol. 45. 33- 41.
  • 19. Himms-Hagen, J. (1967) Sympathetic regulation of metabolism. Pharmacol. Rev. 19. 367-461.
  • 20. Horning, M. G., Williams, E. A., Maling, H. M., Brodie, В. B. (1960) Depot fat as a source of increased liver triglycerides after ethanol. Blochem. Biophys. Research. Comm. 3. 635-640.
  • 21. Hultman, E. (1959) Rapid specific method for determination of aldosaccarides in body fluids. Nature 183. 108-109.
  • 22. LeBlance, J., Nadeau, G. (1961) Urinary excretion of adrenaline and noradrenaline in normal and cold-adapted animals. Can. J. Biochem. Physiol. 39. 215-217.
  • 23. Maling, H. M., Frank, A., Horning, M. G. (1962) Effect of carbon tetrachloride on hepatic synthesis and release of triglycerides. Biochim. Biophys. Acta 64. 540-545.
  • 24. Maling, H. M., Stern, D. N., Altland, P. D., Highman, B., Brodie, В. B. (1966) The physiologic role of the sympathetic nervous system in exercise. J. Pharmacol. Exp. Therap. 154. 35-45.
  • 25. Pikkulangas, A. H., Väänänen, R. V., Savolainen, M. J., Hassinen, I. E. (1982) Precursor supply and hepatic enzyme activities as regulators of triacylglycerol synthesis in isolated hepatocytes and perfused liver. Arch. Biochem. Biophys.. 217. 216-225.
  • 26. Richter, E. A., Sonne, B., Mikines, K. J., Ploug, T., Galbo, H. (1984) Muscle and liver glycogen, protein, and triglycerides in the rat. Effect of exercise and of the sympatho-adrenal system. Eur. J. Appl. Physiol. 52. 346-350.
  • 27. Schotz, M. C., Recknagel, R. O. (1960) Rapid increase of rat liver triglycerides following carbon tetrachloride poisoning. Biochim. Biophys. Acta 41, 151-152.
  • 28. Seitz, H. J., Krone, W., Wilka, H., Tarnowski, W. (1981) Rapid rise in plasma glucagon induced by acute cold exposure in man and rat. Pflügers Arch. 399. 115-122.
  • 29. Takeuchi, A., Kajihara, A,, Suzuki, M. (1977) Effect of acute exposure to cold on the levels of corticosterone and pituitary hormones in plasma collected from free conscious cannulated rats. Endocrinol. Jap. 34. 109-114.
  • 30. Winder, W. W. (1985) Regulation of hepatic glucose production during exercise. Exerc. Sport. Sci. Rev. 13. 1-31.
  • 31. Vernikos, J., Dallman, M. F., Bonner, C., Katzen, A., Shinsako, J. (1982) Pituitary - adrenal function in rats chronically exposed to cold. Endocrinology 110. 413-419.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-cf2aa25d-33df-49aa-8d12-7468bb885a38
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.