Helicobacter pylori infection in type 1 diabetes children and adolescents using 13C urea breath test

• Autorzy: Chobot A. , Bak-Drabik K. , Skala-Zamorowska E. , Krzywicka A. , Kwiecien J. , Polanska J.
• Języki publikacji: EN

Abstrakty

EN

There is a 10–30% prevalence of HP infection in the general pediatric population in Poland. This study aimed to determine its prevalence in T1DM children in Upper Silesia, Poland and estimate its influence on metabolic control of patients. We studied 149(82♀) children with T1DM (duration > 12 months, mean HbA1c) and 298(164♀) age-matched controls. In all cases height and weight z-scores and Cole’s index were assessed. In T1DM patients additionally glycated hemoglobin A1c and T1DM duration were analyzed. Presence of HP infection was determined using 13C-isotope-labeled urea breath test (UBT) (fasting and 30min after ingestion 75 mg of 13C urea). HP infection was present in 17 (11.4%) T1DM patients and in 49 (16.4%) controls (p > 0.05). T1DM patients presented higher values of anthropometric parameters than healthy controls (weight SDS 0.25[–0.46÷0.84] vs. –0.25[–1.06÷0.26], height SDS 0.09[–0.60÷0.69] vs. –0.31[–1.17÷0.48]and Cole’s index 103%[93÷111%] vs. 97%[86÷106%]; for all p < 0001). Within both groups – T1DM children and controls – no differences regarding sex, age and any of the anthropometric parameters were determined. T1DM duration and HbA1c showed no relationto prevalence of HP infection. Prevalence of HP infection in pediatric T1DM patients is similar to that of healthy peers and shows no relation to glycemic control.

Słowa kluczowe

EN

human disease; Helicobacter pylori; human infection; diabetes type 1; child; adolescent; urea breath test

• Wydawca: -
• Czasopismo: Polish Journal of Microbiology
• Rocznik: 2014
• Tom: 63
• Numer: 1
• Opis fizyczny: p.63-67,ref.

Twórcy

autor

Chobot A.

• Clinical Hospital No1, 3 Maja 13–15, 41-800 Zabrze, Poland

autor

Bak-Drabik K.

• Medical University of Silesia, Katowice, Poland

autor

Skala-Zamorowska E.

• Upper Silesian Center of Child’s Health, Katowice, Poland

autor

Krzywicka A.

• Clinical Hospital No1, 3 Maja 13–15, 41-800 Zabrze, Poland

autor

Kwiecien J.

• Medical University of Silesia, Katowice, Poland

autor

Polanska J.

• Data Mining Group, Silesian University of Technology, Gliwice, Poland

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