Modulating effect of lysozyme dimer (KLP-602) on the morphological pattern of hepatopancreas of siberian sturgeon (Acipenser baeri,brandt 1869) following oxytetracycline application

• Autorzy: Wojtacka J. , Szarek, J. , Babinska, I. , Andrzejewska, A.
• Języki publikacji: EN

Abstrakty

EN

Siberian sturgeons were given intraperitoneally 100 mg/kg b.m. of oxytetracycline (OTC) and 24 h after the injection they were immersed in lysozyme dimmer solution (KLP-602) at 100 µg/L of water for 30 min. The effect of OTC, applied separately and in combination with lysozyme dimer, on hepatopancreas morphology has been examined. The results of microscopic and ultrastructural examinations of the organ indicated the existence of morphological lesions following the administration of OTC: congestions and extravasations, parenchymal and lipid-related degeneration, and focal necrosis with relatively frequent infiltrations of lymphoid cells. Ultrastructural examination revealed damage to the mitochondria in hepatocytes. KLP-602 was found to have a protective effect in these changes. Immersion of the fish in an aqueous solution of lysozyme dimer was shown to have an immunomodulating effect, reducing the intensity of morphological changes that resulted from the administration of OTC.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2011
• Tom: 55
• Numer: 2
• Opis fizyczny: p.299-304,fig.,ref.

Twórcy

autor

Wojtacka J.

• Chair of Pathophysiology, Forensic Veterinary Medicine and Administration, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn,Poland

autor

Szarek, J.

autor

Babinska, I.

autor

Andrzejewska, A.

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