The controversy over anti-Helicobacter pylori therapy

• Autorzy: Bocian K.M. , Jagusztyn-Krynicka E.K.
• Języki publikacji: EN

Abstrakty

EN

Helicobacter pylori is a Gram-negative spiral-shaped bacterium, member of ε-Proteobacteria specifically colonizing the gastric epithelium of humans. It causes one of the most common infections worldwide, affecting about half of the world’s population. However, it should be noted that the prevalence of H. pylori, particularly in the Western world, has significantly decreased coinciding with an increase of some autoimmune and allergic diseases, such as asthma. Various epidemiological studies have also documented a negative association between H. pylori colonization and the presence of GERD (gastroesophageal re/ux disease) and risk of esophageal cancer. Additionally, an upward trend of obesity recently observed in inhabitants of developed countries raised a question about the relationship between H. pylori infection and the human body mass index. The first part of this review describes common, recommended anti-H. pylori treatments. The second part, presents the results of recent experiments aimed at evaluating the association between H. pylori infections and gastro-esophageal diseases, the level of stomach hormones, the human body mass index and allergic diseases. Although some studies suggest an inverse association of H. pylori infection with some health problems of the modern world such as asthma, obesity or GERD, H. pylori should be considered as a harmful human pathogen responsible for serious and sometimes lethal diseases. Thus, many scientists advocate the eradication of H. pylori.

Słowa kluczowe

EN

controversy; Helicobacter pylori; therapy; allergy; obesity; neutrophil-activating protein

• Wydawca: -
• Czasopismo: Polish Journal of Microbiology
• Rocznik: 2012
• Tom: 61
• Numer: 4
• Opis fizyczny: p.239-246,ref.

Twórcy

autor

Bocian K.M.

• Department of Bacterial Genetics, Institute of Microbiology, Faculty of Biology, University of Warsaw, Miecznikowa 1, 02-096 Warsaw, Poland

autor

Jagusztyn-Krynicka E.K.

• Department of Bacterial Genetics, Institute of Microbiology, Faculty of Biology, University of Warsaw, Miecznikowa 1, 02-096 Warsaw, Poland

Bibliografia

• Alexander K.A., P.N. Laver, A.L. Michel, M. Williams, P.D. Van Helden, R.M. Warren and N.C. Gey van Pittius. 2010. Novel Mycobacterium tuberculosis complex pathogen, M. mungi. Emerg. Infect. Dis. 16: 1296–1299.
• Augustynowicz-Kopec E., A. Zabost, S. Brzezinska, M. Wasowicz and Z. Zwolska. 2005. Application of the molecular test PCR multiplex for identification of Mycobacterium bovis BCG strains (in Polish). Pneumonol. Alergol. Pol. 73: 228–233.
• Bedwell J., S.K. Kairo, M.A. Behr and J.A. Bygraves. 2001. Identification of substrains of BCG vaccine using multiplex PCR. Vaccine 19: 2146–2151.
• Behr M.A. 2002. BCG-different strains, different vaccines? Lancet Infect Dis. 2: 86–92.
• Bernatowska E., B. Wolska-Kusnierz, M. Pac, M. Kurenko-Deptuch, Z. Zwolska, J.L. Casanova, B. Piatosa, J. van Dongen, K. Roszkowski, B. Mikoluc and others. 2007. Disseminated Bacillus Calmette-Guerin infection and immunodeficiency. Emerging. Infect. Dis. 13: 799–801.
• Brewer T.F. 2000. Preventing tuberculosis with bacillus Calmette-Guérin vaccine: a meta-analysis of the literature. Clin. Infect. Dis. 31: S64–67.
• Brosch R., S.V. Gordon, M. Marmiesse, P. Brodin, C. Buchrieser, K. Eiglmeier, T. Garnier, C. Gutierrez, G. Hewinson, K. Kremer and others. 2002. A new evolutionary scenario for the Mycobacte-rium tuberculosis complex. Proc. Natl. Acad. Sci. USA 99: 3684–3689.
• Corbel M.J., U. Fruth, E. Griffiths and I. Knezevic. 2004. Report on a WHO Consultation on the characterisation of BCG strains, Imperial College, London 15–16 December 2003. Vaccine 22: 2675–2680.
• Cousins D.V., R. Bastida, A. Cataldi, V. Quse, S. Redrobe, S. Dow, P. Duignan, A. Murray, C. Dupont, N. Ahmed and others. 2003.Tuberculosis in seals caused by a novel member of the Mycobacterium tuberculosis complex: Mycobacterium pinnipedii sp. nov. Int. J. Syst. Evol. Microbiol. 53: 1305–1314.
• Gołebiowska M., E. Andrzejewska, I. Stryjewska, H. Baranowska and A. Drazkiewicz. 2008. Advers events following BCG vaccination in infants and children up to 36 months of age (in Polish). Przegl. Epidemiol. 62:71–75.
• Jagielski T., E. Augustynowicz-Kopec and Z. Zwolska. 2010a. Genotyping of Mycobacterium tuberculosis. An overview of the major research techniques (Part I) (in Polish). Pol. Merkur. Lekarski 29: 212–216.
• Jagielski T., E. Augustynowicz-Kopec and Z. Zwolska. 2010b. Genotyping of Mycobacterium tuberculosis. An overview of the major research techniques (Part II) (in Polish). Pol. Merkur. Lekarski 29: 212–216.
• Kasai H., T. Ezaki and S. Harayama. 2000. Di%erentiation of phylogenetically related slowly growing Mycobacteria by their gyrB sequences. J. Clin. Microbiol. 38: 301–308.
• Pankowska A. and J. Rozniecki. 1997. Complications after BCG vaccination in children from Urban area of Lodz in 1994–1995 (in Polish). Pneumonol. Alergol. Pol. 65: 761–766.
• Rodríguez E., L.P. Sánchez, S. Pérez, L. Herrera, M.S. Jiménez, S. Samper and M.J. Iglesias. 2009. Human tuberculosis due to Mycobacterium bovis and M. caprae in Spain, 2004–2007. Int. J. Tuberc. Lung. Dis. 13: 1536–1541.
• Szczuka I. 2002. Adverse events following immunization after BCG vaccination in Poland 1994–2000 (in Polish). Przegl. Epidemiol. 56: 205–216.
• Talbot E.A., D.L. Williams and R. Frothingham. 1997. PCR Identification of Mycobacterium bovis BCG. J. Clin. Microbiol. 35: 566–569.
• Van Ingen J., Z. Rahim, A. Mulder, M.J. Boeree, R. Simeone, R. Brosch, D. van Soolingen. 2012. Characterization of Mycobacterium orygis as M. tuberculosis complex subspecies. Emerg. Infect. Dis. 18: 653–655.
• Van Soolingen D., P.W.M. Hermans, P.E.W. de Haas, D.R. Sol and A. van Embden. 1991. The ocurrence and stability of insertion sequences in Mycobacterium tuberculosis complex strains: evaluation of IS dependent DNA polymorphisms as a tool in the epidemiology of tuberculosis. J. Clin. Microbiol. 29: 2578–2586.
• Venkateswaran K., N. Dohmoto and S. Harayama. 1998. Cloning and nucleotide sequence of the gyrB gene of Vibrio parahaemolyticus and its application in detection of this pathogen in shrimp. Appl. Environ. Microbiol. 64: 681–687.
• Warren R.M., N.C. Gey van Pittius, M. Barnard, A. Hesseling, E. Engelke, M. de Kock, M.C. Gutierrez, G.K. Chege, T.C. Victor, E.G. Hoal and others. 2006. Differentiation of Mycobacterium tuberculosis complex by PCR amplification of genomic regions of difference. Int. J. Tuberc. Lung. Dis. 10: 818–822.
• World Health Organization. Global tuberculosis control: WHO report 2011. Available at: http://whqlibdoc.who.int/publications/2011/9789241564380_eng.pdf
• Yamada S., E. Ohashi, N. Agata, K. Venkateswaran. 1999. Cloning and nucleotide sequence analysis of gyrB of Bacillus cereus, B. thuringiensis, B. mycoides, and B. anthracis and their application to the detection of B. cereus in rice. Appl. Environ. Microbiol. 65: 1483–1490.