Assessment of genomic inbreeding in Polish Konik horses

• Autorzy: Kaminski S. , Hering D.M. , Jaworski Z. , Zabolewicz T. , Rusc A.
• Języki publikacji: EN

Abstrakty

EN

The aim of this study was to assess the inbreeding coefficient of Polish Konik horses based on runs of homozygosity (ROH). Ninety six horses kept in 6 herds located across Poland were genotyped with the use of EquineSNP60 BeadChip (Illumina). SNP markers with a Minor Allele Frequency lower than 0.01 and SNPs assigned to chromosome X or Y were excluded from the study. A total of 50 708 SNPs were included for statistical analysis (SVS software, Golden Helix). The analysis showed that the population is in genetic equilibrium, with Hₑ and Hₒ estimates both equal to 0.3086. Seven categories of Runs of Homozygozity (ROH) length were defined: >0.5, >1, >2, >4, >8, >16, >25 Mb. The genomic inbreeding coefficient derived from ROH (FROH) calculated for each ROH length ranged from 15.96% based on the shortest ROH (>0,5Mb) to 2.71% for the longest ROH (>25Mb). Among individual horses, the inbreeding coefficient ranged from 5.25% to 22.41% (for ROH >1Mb). Analysis of ROH in Polish Koniks allows for more effective management of their inbreeding in the future.

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2017
• Tom: 20
• Numer: 3
• Opis fizyczny: p.603-605,ref.

Twórcy

autor

Kaminski S.

• Department of Animal Genetics, University of Warmia and Mazury, Oczapowskiego 5, 10-719 Olsztyn, Poland

autor

Hering D.M.

• Department of Animal Genetics, University of Warmia and Mazury, Oczapowskiego 5, 10-719 Olsztyn, Poland

autor

Jaworski Z.

• Department of Horse Breeding and Riding, University of Warmia and Mazury, Prawochenskiego 2, 10-719 Olsztyn, Poland

autor

Zabolewicz T.

• Department of Animal Genetics, University of Warmia and Mazury, Oczapowskiego 5, 10-719 Olsztyn, Poland

autor

Rusc A.

• Department of Animal Genetics, University of Warmia and Mazury, Oczapowskiego 5, 10-719 Olsztyn, Poland

Bibliografia

• Ferenčaković M, Hamzić E, Gredler B, Solberg TR, Klemetsdal G, Curik I, Sölkner J (2012) Estimate of autozygosity derived from runs of homozygosity: empirical evidence from selected cattle populations. J Anim Breed Genet 130: 286-293.
• Gurgul A, Szmatoła T, Topolski P, Jasielczuk I, Żukowski K, Bugno-Poniewierska M (2016) The use of runs of homozygosity for estimation of recent inbreeding in Holstein cattle. J Appl Genet 57: 527-530.
• Jezierski T, Jaworski Z (2008) Polish Konik (in German). Westarp Wissenschaften-Verlagsgesellschaft GmbH, Hohenwarsleben, pp 9-16.
• Komosa M, Frąckowiak H, Purzyc H, Wojnowska M, Gramacki A, Gramacki J (2013) Differences in exterior conformation between primitive, Half-bred, and Thoroughbred horses: anatomic-reeding approach. J Anim Sci 91: 1660-1668.
• Mackowski M, Mucha S, Cholewinski G, Cieslak J (2015) Genetic diversity in Hucul and Polish primitive horse breeds. Arch Anim Breed 58: 23-31.
• McQuillan R, Leutenegger A-L, Abdel-Rahman R (2008) Runs of Homozygosity in European Populations. Am J Hum Genet 83: 359-372.
• Pluta M, Osinski Z, Cieśla A, Kolstrung R (2016) Genetic and phenotypic characteristics of Polish Konik horses maintained in the reserve and stable system in central-eastern Poland. Acta Sci Pol Zootechnica 15: 59-76.
• Szwaczkowski T, Greguła-Kania M, Stachurska A, Borowska A, Jaworski Z, Gruszecki TM (2016) Inter- and intra-genetic diversity in the Polish Konik horse: implications for the conservation program. Can J Anim Sci 96: 1-11.

Identyfikatory

DOI

10.1515/pjvs-2017-0074