5’cap-binding site mutations in eIF4E abolish positive effect of the cap on the eIF4E–4E-BP1 interaction

• Autorzy: Modrak-Wojcik A. , Zuberek J. , Stelmachowska A. , Zdanowski K. , Stolarski R.
• Języki publikacji: EN
• Wydawca: -
• Czasopismo: Current Topics in Biophysics. Supplement
• Rocznik: 2016
• Tom: 39
• Numer: A: Posters
• Opis fizyczny: p.48,ref.

Twórcy

autor

Modrak-Wojcik A.

• Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 93 Zwirki and Wigury St., 02-089 Warsaw, Poland

autor

Zuberek J.

• Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 93 Zwirki and Wigury St., 02-089 Warsaw, Poland

autor

Stelmachowska A.

• Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 93 Zwirki and Wigury St., 02-089 Warsaw, Poland

autor

Zdanowski K.

• Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 5A Pawinskiego St., 02-106 Warsaw, Poland
• Institute of Chemistry, University of Natural Sciences and Humanities, 3 Maja 54 St., 08-110 Siedlce, Poland

autor

Stolarski R.

• Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 93 Zwirki and Wigury St., 02-089 Warsaw, Poland

Bibliografia

• [1] Sonenberg, N & Hinnebusch, A.G. (2009). Regulation of translation initiation in eukaryotes: mechanisms and biological targets. Cell 136, 731–745.
• [2] Modrak-Wojcik A., Gorka M., Niedzwiecka K., Zdanowski K., Zuberek J., Niedzwiecka A. & Stolarski R. (2013). Eukaryotic translation initiation is controlled by cooperativity effects within ternary complexes of 4E-BP1, eIF4E, and the mRNA 5’ cap. FEBS Letters 587, 3928–3934.

Identyfikatory

DOI

10.1515/ctb-20163-0003