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2015 | 71 | 06 |

Tytuł artykułu

Wpływ enrofloksacyny, florfenikolu i ceftiofuru na poziom IgY w woreczku żółtkowym oraz surowicy kurcząt

Warianty tytułu

EN
The influence of enrofloxacine, florfenicol, and ceftiofur on IgY in the yolk sac and serum in chicks

Języki publikacji

PL

Abstrakty

EN
Maternal antibodies (matAb) can protect avian embryos and young birds after hatching against vertically transmitted pathogens. In birds, maternal IgY in egg yolk is transferred across the yolk sac through the FcRY receptor to passively immunize chicks. High-affinity binding occurs at pH 6, and does not occur at pH greater than 8.0. This study aimed to evaluate the influence of enrofloxacine, florfenicol, and ceftiofur on maternal IgY concentration in the yolk sac and serum of newly hatched chicks. In this study 184 one-day-old chicks were administered enrofloxacine, florfenicol, or ceftiofur in recommended doses according to the currently recommended treatment schedule. The yolk sac and blood were collected daily from day 1 to day 5 (yolk sac) or 7 (blood) of the experiment. Then, the samples were subjected to radial immunodiffusion investigation. The experiment showed that the concentration of IgY in serum on day 3 after the administration of ceftiofur and florfenicol was higher than that in the control group or the enrofloxacine group. It was also shown that after enrofloxacine treatment the level of IgY was higher in the yolk sac on day 4 of the experiment and lower in serum on day 5 of the experiment compared with the corresponding levels of IgY in the ceftiofur and florfenicol groups. These results suggest that the administration of enrofloxacine, florfenicol, and ceftiofur might influence the efficiency of matAb transfer from the yolk sac to the bloodstream of chicks.

Wydawca

-

Rocznik

Tom

71

Numer

06

Opis fizyczny

s.369-372,rys.,bibliogr.

Twórcy

autor
  • Katedra Epizootiologii z Kliniką Ptaków i Zwierząt Egzotycznych, Wydział Medycyny Weterynaryjnej, Uniwersytet Przyrodniczy we Wrocławiu, pl.Grunwaldzki 45, 50-366 Wrocław
autor
  • Katedra Epizootiologii z Kliniką Ptaków i Zwierząt Egzotycznych, Wydział Medycyny Weterynaryjnej, Uniwersytet Przyrodniczy we Wrocławiu, pl.Grunwaldzki 45, 50-366 Wrocław

Bibliografia

  • 1. Ahmed Z., Akhter S.: Role of maternal antibodies in protection against infectious bursal disease in commercial broilers. Int. J. Poult. Sci. 2003, 2, 251-255.
  • 2. Al-Natour M. Q., Ward L. A., Saif Y. M., Stewart B., Keck L. D.: Effect of different levels of maternally derived antibodies on protection against infectiousbursal disease virus. Avian Dis. 2004, 48, 177-182.
  • 3. East L., Isacke C. M.: The mannose receptor family. Biochim. Biophys. Acta 2002, 1572, 364-386.
  • 4. Ellakany H. F., Abu El-Azm I. M., Bekhit A. A., Shehawy M. M.: Studies on the effects of enrofloxacin overdose on different health parameters in broilerchickens. BS. Vet. Med. J., 5th Scientific Conference, 2007, s. 176-186.
  • 5. Grindstaff J. L., Brodie E. D., Ketterson E. D.: Immune function across generations: integrating mechanism and evolutionary process in maternal antibodytransfer. Proc. R. Soc. B 2003, 270, 2309-2319.
  • 6. Grindstaff J., Hasselquist D., Nilsson J., Sandell M., Smith H. G., Stjernman M.: Transgenerational priming of immunity: maternal exposure toa bacterial antigen enhances offspring humoral immunity. Proc. R. Soc. B2006, 273, 2551-2557.
  • 7. Hamal K. R., Burgess S. C., Pevzner I. Y., Erf G. F.: Maternal antibody transfer from dams to their egg yolks, egg whites, and chicks in meat lines of chickens. Poult. Sci. 2006, 85, 1364-1372.
  • 8. Hasselquist D., Nilsson J. Å.: Maternal transfer of antibodies in vertebrates: trans-generational effects on offspring immunity. Phil. Trans. R Soc B 2009;364, doi: 10.1098/rstb.2008.0137.
  • 9. Lawrence E. C., Arnaudbattandier F., Grayson J., Koski I. R., Dooley N. J.: Ontogeny of humoral immune function in normal chickens – a comparison ofimmunoglobulin-secreting cells in bone-marrow, spleen, lungs and intestine.Clin Exp Immunol 1981, 43, 450-457.
  • 10. Loeken M. R., Roth T. F.: Analysis of maternal IgG subpopulations which are transported into the chicken oocyte. Immunology 1983, 49, 21-28.
  • 11. Lozano G. A., Ydenberg R. C.: Transgenerational effects of maternal immune challenge in tree swallows (Tachycineta bicolour). Can. J. Zool. 2002, 80, 918-925.
  • 12. Mancini G., Carbonara A. O., Heremans J. F.: Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry 1965, 2, 235-254.
  • 13. McCarthy K. M., Yoong Y., Simister N. E.: Bidirectional transcytosis of IgG by the rat neonatal Fc receptor expressed in a rat kidney cell line: a system tostudy protein transport across epithelia. J. Cell Sci. 2000, 113, 1277-1285.
  • 14. Mondal S. P., Naqi S. A.: Maternal antibody to infectious bronchitis virus: Its role in protection against infection and development of active immunity tovaccine. Vet. Immunol. Immunopathol. 2001, 79, 31-40.
  • 15. Nemeth N. M., Oesterle P. T., Bowen R. A.: Am Passive Immunity to West Nile Virus Provides Limited Protection in a Common Passerine Species. J. Trop.Med. Hyg. 2008, 79, 283-290.
  • 16. Pihlaja M., Siitari H., Alatalo R. V.: Maternal antibodies in a wild altricial bird: effects on offspring immunity, growth and survival. J. Anim. Ecol. 2006,75, 1154-1164.
  • 17. Praetor A., Ellinger I., Hunziker W.: Intracellular traffic of the MHC class I-like IgG Fc receptor, FcRn, expressed in epithelial MDCK cells. J. Cell Sci.1999, 112, 2291-2299.
  • 18. Staszewski V., McCoy K. D., Tveraa T., Boulinier T.: Interannual dynamics of antibody levels in naturally infected long-lived colonial birds. Ecology 2007,88, 3183-3191.
  • 19. Tesar D. B., Tiangco N. E., Bjorkman P. J.: Ligand valency affects transcytosis, recycling and intracellular trafficking mediated by the neonatal Fc receptor.Traffic 2006, 7, 1127-1142.
  • 20. Tokarzewski S.: Influence of enrofloxacin and chloramphenicol on the level of IgY in serum and egg yolk after immunostimulation of hens with Salmonella Enteritidis antigens. Pol. J. Vet. Sci. 2002, 5, 151-158.2.
  • 21. West A. P., Herr A. B., Bjorkman P. J.: The chicken yolk sac IgY receptor, a functional equivalent of the mammalian MHC-related Fc receptor, is a phospholipase A2 receptor homolog. Immunity 2004, 20, 601-610.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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