Gruczolakotorbielak sluzowy pecherzyka zolciowego psa - opis przypadku

• Autorzy: Glinska K , Atamaniuk W. , Halon A. , Nicpon J. , Simon K.

Warianty tytułu

EN

Biliary cystadenoma mucinosum in a dog - case report

• Języki publikacji: PL

Abstrakty

EN

Tumours of the gall bladder constitute 4-5% of tumours originating from the bile duct epithelium. The mucous cystadenoma is a rare benign neoplasm of the gall bladder. This study is the case presentation of a male Scottish terrier, aged 12 years. The dog presented weakness, vomiting, loss of appetite and enlargement of the abdominal cavity. The ultrasound examination showed an enlarged gall bladder, filled with heteroechogenic, amorphic contents. By the walls the contents of the bladder were hypoechogenic, about 0.3cm thick. The laboratory blood tests showed leukocytosis, an increase in AST, ALT, GGTP activity and an over 65-fold increase in ALP. In addition, hyperlipidemia was observed in the dog. The following drugs were administered: amoxycyline, ursodexycholic acid, S-adenosine-L-metionin. The control blood tests were performed every three weeks. During the entire period of the therapy significant differences in ALP and ALT activity were observed. After three weeks since the beginning of the therapy ALP activity decreased to the half of the initial value and the significant improvement of the dog’s clinical condition was noted. After the six-month therapy the administration of ursodexycholic acid was stopped for four months. The significant increase in ALP and ALT was observed in this period. Due to the worsening of biochemical blood parameters the therapy with ursodexycholic acid was restarted. On the account of old age and lack of recovery the dog was subjected to euthanasia and autopsy after an eighteen-month therapy. The postmortem examination revealed the normal size liver. The gall bladder was considerably enlarged. The wall of the bladder was irregularly thickened. Based on the histopathological examination, the mucous cystadenoma of the gall bladder was diagnosed.

Słowa kluczowe

PL

nowotwory; psy; gruczolakotorbielak sluzowy; choroby zwierzat; nowotwory pecherzyka zolciowego

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2008
• Tom: 64
• Numer: 11
• Opis fizyczny: s.1314-1316,rys.,fot.,tab.,bibliogr.

Twórcy

autor

Glinska K

• Uniwersytet Przyrodniczy we Wroclawiu, pl.Grunwaldzki 47, 50-366 Wroclaw

autor

Atamaniuk W.

autor

Halon A.

autor

Nicpon J.

autor

Simon K.

Bibliografia

• 1. Center S. A., Slater M. R., Manwarren T., Prymak K.: Diagnostic efficacy of serum alkaline phospathase and γ-glutamyltransferase in dogs with histologically confirmed hepatobiliary disease: 270 cases (1980-1990). J. Am. Vet. Med. Assoc. 1992, 201, 1258-1264.
• 2. Davis W., Chow M., Nagornney D.: Extrahepatic biliary cystadenomas and cystadenocarcinomas. Ann. Surg. 1995, 222, 619-625.
• 3. Devaney K., Googman Z. D., Ishak K. G.: Hepatobiliary cystadenoma and cystadenocarcinoma. Am. J. Surg. Pathol. 1994, 18, 1078-1091.
• 4. Fahie M. A., Martin R. A.: Extrahepatic biliary tract obstruction: a retrospective study of 45 cases (1983-1993). J. Am. Anim. Hosp. Assoc. 1995, 31, 478-482.
• 5. Glińska K., Nicpoń J., Hildebrand W.: Kwas ursodeoksycholowy w terapii chorób wątroby psów. Medycyna Wet. 2005, 61, 911-913.
• 6. Leibman N. F., Larson V. S., Ogilvie G. K.: Oncologic diseases of the digestive system, [w:] Tams T. R.: Handbook of Small Animal Gastroenterology. Saunders, St. Louis 2003, 370-415.
• 7. Tsiftsis D., Christodoulakis M., de Bree E., Sanidas E.: Primary intrahepatic biliary cystadenomatous tumors. J. Surg. Oncol. 1997, 64, 341-346.
• 8. Wheeler D. A., Edmondson H. A.: Cystadenoma with mesenchymal stroma (CMS) in the liver an bile ducts. Cancer 1985, 56, 1434-1445.
• 9. Withrow S. J.: Cancer of the gastrointestinal tract, [w:] Withrow S. J., Mac-Ewen E. G. Small Animal Clinical Oncology, Saunders W. B. Company, Philadelphia 2001, 305-353.