Beta[1-3]-glucan exposure levels among workers in four British Columbia sawmills

• Autorzy: Ronald L. A. , Davies H.W. , Bartlett K.H. , Kennedy S.M. , Teschke K. , Spithoven J. , Dennekamp M. , Demers P.A.
• Języki publikacji: EN

Abstrakty

EN

B(1→3)-glucans were extracted from wood dust samples taken during the summer of 1997 at four British Columbia sawmills. Personal dust samples were collected using a GSP-sampler for inhalable dust and the sampling strategy targeted all production and maintenance jobs at least once at each mill. Potential exposure determinants data were documented concurrently, including weather conditions, log storage methods, wood conditions, species, production level, jobs and tasks. B(1→3)-glucans were measured by enzyme inhibition immunoassay (EIA). A total of 223 personal B(1→3)-glucan samples were analyzed. 45.7% were below the limit of detection (LOD). Geometric mean concentration ranged from 3.5 to 18.9 µg/m3 across the four mills. The highest levels were measured at the Interior mills, particularly in the log processing and sawmill areas. Multivariate regression models indicated that land-based log storage, clean-up jobs, high wood dust concentration, lumber yard department and the interaction between land-based log storage method and log processing department were associated with increased B(1→3)-glucan concentration.

Słowa kluczowe

EN

occupational exposure; occupational hazard; British Columbia; occupational medicine; sawmill; wood dust; worker; bioaerosol; glucan

• Wydawca: -
• Czasopismo: Annals of Agricultural and Environmental Medicine
• Rocznik: 2003
• Tom: 10
• Numer: 1
• Opis fizyczny: p.21-29

Twórcy

autor

Ronald L. A.

• University of British Columbia, 2206 East Mall, Vancouver, BC, V6T 1Z3 Canada

autor

Davies H.W.

autor

Bartlett K.H.

autor

Kennedy S.M.

autor

Teschke K.

autor

Spithoven J.

autor

Dennekamp M.

autor

Demers P.A.

Bibliografia

• 1. Alwis KU, Mandryk J, Hocking AD: Exposure to biohazards in wood dust: bacteria, fungi, endotoxins, and (1→3)-beta-D-glucans. Appl Occup Environ Hyg 1999, 14(9), 598-608.
• 2. Belin L: Sawmill alveolitis in Sweden. Int Arch Allergy Appl Immunol 1987, 82(3-4), 440-443.
• 3. Conrad DJ, Warnock M, Blanc P, Cowan M, Golden JA: Microgranulomatous aspergillosis after shoveling wood chips: report of a fatal outcome in a patient with chronic granulomatous disease. Am J Ind Med 1992, 22(3), 411-418.
• 4. Cote J, Chan H, Brochu G, Chan-Yeung M: Occupational asthma caused by exposure to neurospora in a plywood factory worker. Br J Ind Med 1991, 48(4), 279-282.
• 5. Dahlqvist M, Ulfvarson U: Acute effects on forced expiratory volume in one second and longitudinal change in pulmonary function among wood trimmers. Am J Ind Med 1994, 25(4), 551-558.
• 6. Demers P, Kennedy S, Teschke K, Davies H, Bartlett K, Leung V, Tang C: Study of respiratory health among sawmill workers. Final report to the Washington State Department of Labour and Industries, Vancouver 1997.
• 7. Demers P, Kennedy S, Teshke K, Leung V, Bartlett K, Davies H, Tang C: Study of Respiratory Health among Sawmill Workers. Final report - Pilot Study Sampling Results. Finding Solutions. Research at the Workers' Compensation Board of B.C., Richmond, B.C. 1997.
• 8. Demers PA, Teschke K, Kennedy SM: What to do about softwood? A review of respiratory effects and recommendations regarding exposure limits. Am J Ind Med 1997, 31(4), 385-398.
• 9. Dennekamp M, Demers P, Bartlett K, Davies H, Teschke K: Endotoxin exposure among softwood lumber mill workers in the Canadian province of British Columbia. Ann Agric Environ Med 1999, 6, 141-146.
• 10. Douwes J, Doekes G, Montijn R, Heederik D, Brunekreef B: Measurement of beta(1:-glucans in occupational and home environments with an inhibition enzyme immunoassay. Appl Environ Microbiol 1996, 62(9), 3176-3182.
• 11. Douwes J, McLean D, van Der Maarl E, Heederik D, Pearce N: Worker exposures to airborne dust, endotoxin and beta(1,3)-glucan in two New Zealand sawmills. Am J Ind Med 2000, 38(4), 426-430.
• 12. Dutkiewicz J: Bacteria, fungi and endotoxin in stored timber logs and airborne sawdust in Poland. In: O’Rear CE, Llewellyn GC: Biodeterioration Research 2: General Biodeterioration, Degradation, Mycotoxins, Biotoxins, and Wood Decay, 533-547. Plenum Press, New York 1989.
• 13. Dutkiewicz J, Sorenson W, Lewis D, Olenchock S: Microbial Contaminants of Stored Timber as Potential Respiratory Hazards for Sawmill Workers. VIIth International Pneumoconioses Conference, Pittsburgh, Pennsylvania, 23-26 August 1988, 712-716, NIOSH.
• 14. Dykewicz MS, Laufer P, Patterson R, Roberts M, Sommers HM: Woodman's disease: hypersensitivity pneumonitis from cutting live trees. J Allergy Clin Immunol 1988, 81(2), 455-460.
• 15. Eduard W, Heederik D: Methods for quantitative assessment of airborne levels of noninfectious microorganisms in highly contaminated work environments. Am Ind Hyg Assoc J 1998, 59(2), 113-127.
• 16. Eduard W, Sandven P, Levy F: Exposure and IgG Antibodies to Mold Spores in Wood Trimmers: Exposure-Response Relationships With Respiratory Symptoms. Appl Occup Environ Hyg 1994, 9(1), 44-48.
• 17. Enarson DA, Chan-Yeung M: Characterization of health effects of wood dust exposures. Am J Ind Med 1990, 17(1), 33-38.
• 18. Goldsmith DF, Shy CM: Respiratory health effects from occupational exposure to wood dusts. Scand J Work Environ Health 1988, 14(1), 1-15.
• 19. Goto H, Yuasa K, Rylander R: (1→3)-beta-D-glucan in indoor air, its measurement and in vitro activity. Am J Ind Med 1994, 25(1), 81-83.
• 20. Halpin DM, Graneek BJ, Turner-Warwick M, Newman Taylor AJ: Extrinsic allergic alveolitis and asthma in a sawmill worker: case report and review of the literature. Occup Environ Med 1994, 51(3), 160-164.
• 21. Hornung R, Reed L: Estimation of Average Concentration in the Presence of Nondetectable Values. Appl Occup Environ Hyg 1990, 5(1), 46-51.
• 22. Jagels R: Health hazards of natural and introduced chemical components of boatbuilding woods. Am J Ind Med 1985, 8(3), 241-251.
• 23. Jappinen J, Haahtela T, Liira J: Chip pile workers and mold exposure. Allergy 1987, 42, 545-548.
• 24. Kolmodin-Hedman B, Blomquist G, Lofgren F: Chipped wood as a source of mould exposure. Eur J Respir Dis Suppl 1987, 154, 44-51.
• 25. Miyazaki T, Kotaro S, Mitsutake K, Maesaki S, Tanaka K, Hara K: (1→)-B-D-Glucan in Culture Fluid of Fungal Activates Factor G, a Limulus Coagulation Factor. J Clin Lab Anal 1995, 9, 334-339.
• 26. Rask-Andersen A: Chapter 17: Inhalation Fever. In: Harber PS, Balmes JR: Occupational and Environmental Respiratory Disease, 243-258. Mosby-Year Book Inc., St. Louis, MO 1995.
• 27. Rask-Andersen A, Land CJ, Enlund K, Lundin A: Inhalation fever and respiratory symptoms in the trimming department of Swedish sawmills. Am J Ind Med 1994, 25(1), 65-67.
• 28. Rylander R, Norrhall M, Engdahl U, Tunsater A, Holt PG: Airways inflammation, atopy, and (1: -beta-D-glucan exposures in two schools. Am J Respir Crit Care Med 1998, 158(5 Pt 1), 1685-1687.
• 29. Rylander R, Thorn J, Attefors R: Airways inflammation among workers in a paper industry. Eur Respir J 1999, 13(5), 1151-1157.
• 30. Schlueter DP, Fink JN, Hensley GT: Wood-pulp workers’ disease: a hypersensitivity pneumonitis caused by Alternaria. Ann Intern Med 1972, 77(6), 907-914.
• 31. Teschke K, Demers PA, Davies HW, Kennedy SM, Marion SA, Leung V: Determinants of exposure to inhalable particulate, wood dust, resin acids, and monoterpenes in a lumber mill environment. Ann Occup Hyg 1999, 43(4), 247-255.
• 32. Teschke K, Ostry A, Hertzman C, Demers PA, Barroetavena MC, Davies HW, Dimich-Ward H, Heacock H, Marion SA: Opportunities for a broader understanding of work and health: multiple uses of an occupational cohort database. Can J Public Health 1998, 89(2), 132-136.
• 33. Thorn J, Beijer L, Rylander R: Airways inflammation and glucan exposure among household waste collectors. Am J Ind Med 1998, 33(5), 463-470.
• 34. Van Assendelft AH, Raitio M, Turkia V: Fuel chip-induced hypersensitivity pneumonitis caused by penicillium species. Chest 1985, 87(3), 394-396.
• 35. Wenzel FJ, Emanuel DA: The epidemiology of maple bark disease. Arch Environ Health 1967, 14(3), 385-389.
• 36. Winandy JE: Wood properties. In: Arntsen CJ: Encyclopedia of Agricultural Science, 549-561. Orlando, FL 1994.
• 37. Zabel RA, Morrell JJ: Wood Microbiology-Decay and its Prevention. Academic Press Inc., New York 1992.