Identification of a novel protein encoded by third conserved gene within RAG locus

• Autorzy: Kasztura M. , Miazek A. , Cebrat M. , Kisielow P.
• Języki publikacji: EN

Abstrakty

EN

 Recently, a third evolutionarily conserved gene, NWC, was discovered within the recombination activating gene (RAG) locus, known to contain the RAG1 and RAG2 genes. Here, we identify and characterize the murine endogenous NWC protein which has no homology to any known protein and is ubiquitously expressed. In the cell, the NWC protein which has been suggested to function as a transcriptional repressor, is found in the cytoplasm as well as in the nucleus.

Słowa kluczowe

EN

protein; tissue distribution; monoclonal antibody; mouse; RAG2 gene; lymphocyte; RAG1 gene; recombination activating gene; intracellular distribution; mice; evolutionarily conserved protein; T cell

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2009
• Tom: 56
• Numer: 1
• Opis fizyczny: p.177-181,fig.,ref.

Twórcy

autor

Kasztura M.

• Polish Academy of Sciences, Wroclaw, Poland

autor

Miazek A.

autor

Cebrat M.

autor

Kisielow P.

Bibliografia

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