Ocena zmian patomorfologicznych skory swinek morskich leczonych itrakonazolem po zakazeniu grzybem Trichophyton mentagrophytes

• Autorzy: Piorkowski J

Warianty tytułu

EN

Estimation of pathomorphological skin changes in guinea pigs after itraconazole treatment during infection with Trichophyton mentagrophytes

• Języki publikacji: PL

Abstrakty

EN

The aim of the research was to investigate the possibility of using oral medicines for the treatment of animals with skin mycoses. The administration of oral azole antifungal Itraconazole was conducted on guinea pigs. In the light microscopy investigation during treatment of guinea pigs with Itraconazole, mycelium were not observed 4 days after the time of the administration of the drug, both in the stratum corneum of the epidermis and in hair sheaths. Neither was mycelium confirmed in the subcutaneous layer. Only parakeratose, hyperkeratose was observed, as well as a small degree of akantose. The investigation with the use scanning microscope made it possible to additionally affirm the presence on the top of scraps of spherical forms the accumulations of drops of fat which is characteristic for azole antifungals. The administration of oral azole antifungal causes the rapid regression of pathological changes in the deep layers of the skin. Therapy of this type can be useful in veterinary medicine.

Słowa kluczowe

PL

choroby skory; zmiany patomorfologiczne; itrakonazol; grzybica skory; Trichophyton mentagrophytes; leczenie; skora; swinki morskie; grzybice

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2008
• Tom: 64
• Numer: 04A
• Opis fizyczny: s.450-453,fot.,bibliogr.

Twórcy

autor

Piorkowski J

• Akademia Rolnicza w Lublinie, ul.Gleboka 30, 20-612 Lublin

Bibliografia

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