Wieloopornosc na leki przeciwbakteryjne paleczek Salmonella enterica subsp. enterica izolowanych w Polsce w latach 1998-2000

• Autorzy: Szych J. , Cieslik A. , Paciorek J. , Kaluzewski S.
• Języki publikacji: PL

Abstrakty

PL

Określono wrażliwość na antybiotyki i chemioterapeutyki 510 szczepów pałeczek Salmonella enterica subsp. enterica reprezentujących 56 serotypów, izolowanych w latach 1998 - 2000 z próbek kału ludzi chorych i zdrowych oraz próbek żywności i ścieków. Stwierdzono, że 42,9% szczepów było opornych na 2 lub więcej antybiotyków (szczepy MDR). Oporne szczepy należały głównie do serotypów Typhimurium, Hadar i Virchow. Wykryto dwa szczepy Salmonella wytwarzające ESBL

EN

A total of 510 Salmonella enterica subsp. enterica strains representing 56 serotypes, isolated from human stool specimens during 1998-2000 in sanitary-epidemiological units in Poland were tested for their susceptibility by a standard disk diffusion method for: ampicillin, cefotaxime, chloramphenicol, tetracycline, streptomycin, gentamicin, kanamycin, nalidixic acid, ciprofloxacin, furayolidone, cotrimoxazole, sulfonamides and trimethoprim. For 201 of the investigated strains, belonging to 5 most common isolated serotypes (S. Enteritidis, S. Typhimurium, S. Hadar, S. Infantis and S. Virchow) the minimal inhibitory concentrations (MICs) for the aforementioned antibiotic, as well as for amoxicillin with clavulanian were determined. Selected strains were screened for production extended spectrum b-lactamases (ESBLs). It was observed that 42.9% of Salmonella enterica subsp. enterica strains were resistant to 2 or more antibiotics, with the highest prevalence of MDR strains among serotypes Typhimurium, Hadar and Virchow, Resistance to ampicillin, streptomycin, tetracycline, nalidixic acid, furayolidone and sulphonamides was observed most frequently. Over 93% of S. Virchow strains were resistant to furazolidone. No strains resistant to ciprofloxacin were detected according to the NCCLS guidelines, but 31.3% of isolates exhibiting reduced ciprofloxacin susceptibility (MICs ranging between 0.125 and 0.5 mg/1). Two strains S. Mbandaka and Salmonella group D (variant motility -) were resistant to cefotaxime and probably produced ESBL.

Słowa kluczowe

PL

izolowanie; infekcja bakteryjna; lekoopornosc; kal; zywnosc; opornosc na antybiotyki; wrazliwosc na chemioterapeutyki; ludzie zdrowi; wrazliwosc na antybiotyki; choroby przewodu pokarmowego; Salmonella enterica; scieki; bakteriologia; bakterie; ludzie chorzy

• Wydawca: -
• Czasopismo: Medycyna Doświadczalna i Mikrobiologia
• Rocznik: 2001
• Tom: 53
• Numer: 1
• Opis fizyczny: s.17-29,tab.,bibliogr.

Twórcy

autor

Szych J.

• Panstwowy Zaklad Higieny, 00-791 Warszawa, ul.Chocimska 24

autor

Cieslik A.

autor

Paciorek J.

autor

Kaluzewski S.

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