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2008 | 64 | 03 |

Tytuł artykułu

Choroby prosiat wywolane przez przetrwalnikujace beztlenowce

Warianty tytułu

EN
Pig diseases caused by sporing clostridia

Języki publikacji

PL

Abstrakty

EN
Three species of the genus Clostridium play a significant role in causing pig diseases. These are: Clostridium (C.) perfringens type-C, C. perfringens type-A and C. difficile. The most important is C. perfringens type-C which is the etiological agent of infectious, necrotic enteritis of young piglets, causing necrosis of the mucosa in the small intestine and sometimes also in the cecum and proximal portion of the colon. The beta-toxin, also called CPB, produced by this microorganism is the main factor in causing in the mentioned tissue damage and death, usually in a high percentage of the newly born piglets. Differences in the pathogenesis and clinical picture between enteric disease caused by the type C and type A of C. perfringens are presented. The A-type produces the alpha toxin also called the CPA-toxin but not the CPB-toxin. The discovery of CPA in the intestinal contents of the small intestine, in the absence of other enteric pathogens, is the most reliable criterion for the diagnosis of C. perfringens, type A infection. It is supported by demonstrating the production by the isolated C. perfringens type-A of the beta 2 (CPB2) toxin. C. difficile is the etiological agent of Clostridium difficile-associated disease (CDAD). This disease is observed in piglets 1-7 days of age and is characterized by scour, rarely accompanied by respiratory symptoms. Essential in the pathogenesis are toxins A (TcdA) and B (TcdB). Their demonstration in the feces and intestinal content is the basis for the diagnosis of CDAD.

Wydawca

-

Rocznik

Tom

64

Numer

03

Opis fizyczny

s.253-256,fot.,tab.,bibliogr.

Twórcy

  • Panstwowy Instytut Weterynaryjny - Panstwowy Instytut Badawczy, Al.Partyzantow 57, 24-100 Pulawy
autor

Bibliografia

  • 1. Bergeland M. E.: Pathogenesis and immunity of Clostridium perfringens type C enteritis in swine. J. Am. Vet. Med. Assoc. 1972, 160, 158.
  • 2. Bueschel D. M., Jost B. H., Billngton S. J.: Prevalence of cpb 2 encoding beta 2 toxin, in Clostridium perfringens field isolates: correlation of genotype with phenotype. Vet. Microbiol. 2003, 94, 121-129.
  • 3. Collins J. E., Bergeland M. E., Bouley D.: Diarrhea associated with Clostridium perfringens type A enterotoxin in neonatal pigs. J. Vet. Diagn. Invest. 1989, 1, 351-353.
  • 4. Cygan Z. M.: Choroby beztlenowcowe zwierząt. Wyd. Pol-Druk, Kraków 1999.
  • 5. Dafwang I., Ricke S. C., Schaefer D. M.: Evaluation of some commercial media for the cultivation and enumeration of Clostridium perfringens from the chick intestine. Poult. Sci. 1987, 66, 652-658.
  • 6. Estrada-Correa A. E., Taylor D. J.: Clostridium perfringens A spores, enterotoxin and antibody to enterotoxin. Vet. Rec. 1989, 124, 606-611.
  • 7. Gilbert M., Jolivet-Renaud C., Popoff M. R.: Beta 2 toxin, a novel toxin produced by Clostridium perfringens. Gene 1997, 203, 65-73.
  • 8. Hogh P.: Necrotizing infectious enteritis in piglets caused by Clostridium perfringens type C. II. Incidence and clinical features. Acta Vet. Scand. 1967, 8, 301.
  • 9. Jestin A., Popoff M. R., Mahe S.: Epizootiologic investigations of diarrheic syndrome in fattening pigs. Am. J. Vet. Res. 1985, 46, 2149-2151.
  • 10. Johannsen U., Menger S., Arnold P.: Untersuchungen zur experimentellen Clostridium perfringens Typ A Enterotoxaemia der Saugferkel. Mntsh. Vet. Med. 1993, 48, 267-273.
  • 11. Meer R. R., Songer J. G.: Multiplex PCR method for genotyping Clostridium perfringens. Am. J. Vet. Res. 1997, 58, 702-705.
  • 12. Pejsak Z., Cygan Z., Buczek J.: Rola beztlenowców C. novyi w nagłych padnięciach świń. Medycyna Wet. 2000, 56, 39-42.
  • 13. Pejsak Z.: Ochrona zdrowia świń. Polskie Wydawnictwo Rolnicze, Poznań 2007.
  • 14. Popoff M. R.: Enteropathogenicity of purified Clostridium perfringens enterotoxin in pigs. Am. J. Vet. Res. 1985, 46, 2147-2148.
  • 15. Songer J. G.: Clostridial enteric disease of domestic animals: a review. Clin. Microbiol. Rev. 1996, 9, 216-234.
  • 16. Songer J. G., Post K. W., Larson D. J.: Enteric infection of neonatal swine with Clostridium difficile. Swine Health Produc. 2000, 8, 185-189.
  • 17. Songer J. G., Uzal F. A.: Clostridial enteric infections in pigs. J. Vet. Diagn. Invest. 2005, 17, 528-536.
  • 18. Straw B. E., Zimmerman J. J., D'Allaire, Taylor D.: Diseases of Swine. 2006.
  • 19. Walker P. D., Murell T. G. C., Nagy L. K.: Scanning electron microscopy of the jejunum in enteric necroticans. J. Med. Microbiol. 1980, 13, 445.
  • 20. Wasiński B., Pejsak Z.: Cechy fenotypowe i genotypowe szczepów Clostridium perfringens izolowanych od prosiąt ssących. Medycyna Wet. (w druku).
  • 21. Waters E. H., Orr J. P., Clark E. G., Schaufele C. M.: Typhlocolitis caused by Clostridium difficile in suckling piglets. J. Vet. Diagn. Invest. 1998, 10, 104-108.

Typ dokumentu

Bibliografia

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Identyfikator YADDA

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