Interaction of organo-tin derivatives with gramicidin ion-conducting channel

• Autorzy: Radecka H
• Języki publikacji: EN

Abstrakty

EN

The objective of this study was to determine the interaction of organo tin (IV) compounds with a gramicidin ion-conducting channel incorporated into planar lipid bilayers. The relative change of trans membrane current was used as a parameter for estimation the above interaction. This measured parameter was in good relationship with physicochemical (logP) and topological (TSA) properties of the compounds under study. The presented model might be apply for estimation of toxicity of organo metallic derivatives.

Słowa kluczowe

EN

organo-metallic derivative; toxicity; tin; lead; living organism; gramicidin; triphenyltin chloride; trimethyltin chloride; gramicidin ion-conducting channel

• Wydawca: -
• Czasopismo: Polish Journal of Environmental Studies
• Rocznik: 2000
• Tom: 09
• Numer: 5
• Opis fizyczny: p.419-422,fig.,ref.

Twórcy

autor

Radecka H

• Polish Academy of Sciences, Tuwima 10, 10-747 Olsztyn, Poland

Bibliografia

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