Obnizona wrazliwosc na triklosan metycylinoopornych gronkowcow zlocistych

• Autorzy: Wisniewska K. , Piechowicz L. , Galinski J.

Warianty tytułu

EN

Reduced susceptibility to triclosan in methicillin - resistant Staphylococcus aureus

• Języki publikacji: PL

Abstrakty

PL

U 62% szczepów MRSA stwierdzono obniżoną wrażliwość na triklosan (MIC 2mg/L), podczas gdy szczepy MSSA na ogól (93%) charakteryzowały się wysoką wrażliwością na ten związek (MIC 0,031mg/L). Większość szczepów MRSA o obniżonej wrażliwości na triklosan miało taki sam wzór leko- oporności. Obniżona wrażliwość na triklosan występowała u 8 spośród 9 szczepów MRSA wysokoopornych na mupirocynę i najczęściej towarzyszyła oporności na kwas fusydowy.

EN

Susceptibility to triclosan in Staphylococcus aureus was determined. The study was carried out on 200 strains, including 100 resistant (MRSA) and 100 susceptibile (MSSA) to methicillin. The examined strains were isolated from varied clinical samples and patients in 18 medical centers, in majority from hospitals in the region of Gdansk. The susceptibility was estimated by the MIC (minimal inhibitory concentration) using dilution test in Mueller - Hinton agar. The antimicrobial resistance patterns were determined, including resistance to methicillin and inupirocin. The most of MRSA strains (62%) demonstrated reduced susceptibility to triclosan (MIC 2mg/L), while 93 % of MSSA strains were highly sensitive to this antibacterial agent (MIC 0,031 mg/L). The majority (66,1%) of MRSA strains with reduced susceptibility to triclosan demonstrated the same antimicrobial resistance pattern. Reduced susceptibility to triclosan was observed in 8 from 9 high - level mupirocin resistant strains, but the most of MRSA strains with reduced triclosan susceptibility (91,5%) were found among fusidic acid resistant strains.

Słowa kluczowe

PL

gronkowiec zlocisty; Staphylococcus aureus; szczepy bakteryjne; opornosc na antybiotyki; metycylina; mupirocyna; wrazliwosc na leki; triklosam

• Wydawca: -
• Czasopismo: Medycyna Doświadczalna i Mikrobiologia
• Rocznik: 2006
• Tom: 58
• Numer: 1
• Opis fizyczny: s.11-17,rys.,tab.,bibliogr.

Twórcy

autor

Wisniewska K.

• Akademia Medyczna w Gdansku, ul.Do Studzienki 38, 80-227 Gdansk

autor

Piechowicz L.

autor

Galinski J.

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