Improving the efficiency of halogenated benzimidazole inhibitors of protein kinase CK2

• Autorzy: Meggio F , Pagano M.A. , Andrzejewska M. , Cesaro L. , Kazimierczuk Z. , Pinna L.A.
• Języki publikacji: EN

Słowa kluczowe

EN

subunit; benzimidazole inhibitor; protein kinase; efficiency

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 2003
• Tom: 08
• Numer: 2A
• Opis fizyczny: p.594-595

Twórcy

autor

Meggio F

• University of Padova, Padova, Italy

autor

Pagano M.A.

autor

Andrzejewska M.

autor

Cesaro L.

autor

Kazimierczuk Z.

autor

Pinna L.A.

Bibliografia

• 1. Pinna, L.A. Casein kinase 2: an 'eminence grise' in cellular regulation? Biochim. Biophys. Acta 1054 (1990) 267-284.
• 2. Guerra, B. and Issinger, O.-G. Protein kinase CK2 and its role in cellular proliferation, development and pathology. Electrophoresis 20 (1999) 391-408.
• 3. Meggio, F. and Pinna, L.A. One-thousand-and-one substrates of protein kinase CK2? FASEB J. (2003) in press.
• 4. Ahmed, K., Gerber, D.A. and Cochet, C. Joining the cell survival squad: an emerging role for protein kinase CK2. Trends Cell Biol. 12 (2002) 226-230.
• 5. Pinna, L.A. Protein kinase CK2: a challenge to canons. J. Cell Sci. 115 (2002) 3873-3878.
• 6. Szyszka, R., Grankowski, N., Felczak, K. and Shugar, D. Halogenated benzimidazoles and benzotriazoles as selective inhibitors of protein kinases CK I and CK II from Saccharomyces cerevisiae and other sources. Biochem. Biophys. Res. Commun. 208 (1995) 418-424.
• 7. Sarno, S., Reddy, H., Meggio, F., Ruzzene, M., Davies, S.P., Donella-Deana, A., Shugar, D. and Pinna, L.A. Selectivity of 4,5,6,7- tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2'). FEBS Lett. 496 (2001) 44-48.
• 8. Battistutta, R., De Moliner, E., Sarno, S., Zanotti, G. and Pinna, L.A. Structural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazole. Protein Sci. 10 (2001) 2200-2206.