Analysis of the murein of a Listeria monocytogenes EGD mutant lacking functional penicillin binding protein 5 [PBP5]

• Autorzy: Korsak D , Popowska M. , Markiewicz Z.
• Języki publikacji: EN

Abstrakty

EN

Cells of a mutant of Listeria monocytogenes lacking functional PBP5, an enzyme with DD-carboxypeptidase activity, make thicker cells walls. In this study we show that the muropeptide profile of the mutant, obtained after HPLC analysis of a muramidase digest of cell wall murein, differs from that for the wild type strain. The main differences embrace strongly reduced disaccharide-tripeptide content, strongly increased amounts of pentapeptide-containing muropeptides and a shift in profile from less cross-linked muropeptides (monomers, dimers) towards more highly cross-linked ones.

Słowa kluczowe

EN

cell; Listeria monocytogenes; muropeptide profile; penicillin binding protein; murein; mutant

• Wydawca: -
• Czasopismo: Polish Journal of Microbiology
• Rocznik: 2005
• Tom: 54
• Numer: 4
• Opis fizyczny: p.339-342,fig.,ref.

Twórcy

autor

Korsak D

• Warsaw University, Miecznikowa 1, 02-096 Warsaw, Poland

autor

Popowska M.

autor

Markiewicz Z.

Bibliografia

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