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Czasopismo

1992 | 37 | 1 |

Tytuł artykułu

Changes in intestinal permeability to 51Cr - ethylene - diaminetetraacetate [51Cr-EDTA] in animal infected with gastrointestinal nematodes

Autorzy

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Permeability of the intestine to ⁵¹Cr-EDTA administered intragastrically was assessed in mice infected with Trichinella spiralis, in gerbils infected with Trichostrongylus colubriformis and in rabbits infected with Obeliscoides cuniculi. The results showed that, compared with the worm-free control animals, there was a significant increase in the recovery of ⁵¹Cr-EDTA in the urine five hours after the administration of the ⁵¹Cr-EDTA in all infected animals, about six times more in mice, ten times more in gerbils, and five times more in rabbits. Increased gut permeability appeared to be associated with changes in the mucosal surface of the gut, directly related to the action of the worms on the epithelium.

Słowa kluczowe

Wydawca

-

Czasopismo

Rocznik

Tom

37

Numer

1

Opis fizyczny

p.41-45,fig.

Twórcy

autor
  • Department of Parasitology, Zoological Institute, University of Warsaw, 00-927 Warsaw, Poland
autor
  • Department of Parasitology, Zoological Institute, University of Warsaw, 00-927 Warsaw, Poland
autor
  • Department of Veterinary Physiology, University of Glasgow Veterinary School, Glasgow G61 1QH, Scotland, U.K.

Bibliografia

  • Barker I. K. 1973. Scanning electron microscopy of the duodenal mucosa of lambs infected with Trichostrongylus colubriformis. Parasitology, 67, 307-314.
  • Bell R. G., McGregor D. D., Despommier D. D. 1979. Trichinella spiralis: mediation of the intestinal component of protective immunity in the rat by multiple, phase-specific, antiparasitic responses. Experimental Parasitology, 47, 140-157.
  • Bjarnason I., O’Morain C., Levi A. J., Peters T. J. 1983. Absorption of ⁵¹chromium-labelled ethylenediamine-tetraacetate in inflammatory bowel disease. Gastroenterology, 85, 318-322.
  • Bjarnason I., Marsh M. N., Price A., Levi A. J., Peters T. J. 1985. Intestinal permeability in patients with coeliac disease and dermatitis herpetiformis. Gut, 26, 1214-1219.
  • Coop R. L., Angus K. W. 1975. The effect of continuous doses of Trichostrongylus colubriformis larvae on the intestinal mucosa of sheep and on liver vitamin A concentration. Parasitology, 70, 1-9.
  • Dargie J. D. 1975. Applications of radioisotopic techniques to the study of red cell and plasma protein metabolism in helminth diseases of sheep. In: Pathogenic processes in parasitic infections. Symposia of the British Society for Parasitology, (Eds. A. E. R. Taylor and R. Muller). Blackwell Scientific Publications, Oxford, 13, 50-52.
  • Holmes P. H., Maclean J. M. 1971. The pathophysiology of ovine ostertagiasis: a study of the changes in plasma protein metabolism following single infections. Research in Veterinary Science, 12, 265-271.
  • Jenkins R. T., Goodacre R. L., Reilly R. M., Hunt R. H., Bienenstock J. 1985. Intestinal permeability in Crohn's disease, ulcerative colitis and gluten-sensitive enteropathy. Gastroenterology, 88, 1433.
  • Maclean J. M., Lewis D., Holmes P. H. 1987. The pathogenesis of benzimidazole-resistant and benzimidazole-susceptible strains of Trichostrongylus colubriformis in the Mongolian gerbil (Meriones unguiculatus). Journal of Helminthology, 61, 179-189.
  • Maclean J. M., Siński E., Holmes P. H. 1989. Intestinal permeability to ⁵¹Cr-ethylenediaminetetraacetate (⁵¹Cr-EDTA) in animals infected with Trichostrongylus colubriformis. Acta Parasitologica Polonica, 34, 191-198.
  • Martin J. 1980. Scanning electron microscope studies of the small intestine of rats maintained on a low protein diet and infected with Nippostrongylus brasiliensis. Parasitology, 80, 39-47.
  • Miller H. R. P. 1984. The protective mucosal response against gastrointestinal nematodes in ruminants and laboratory animals. Veterinary Immunology and Immunopathology, 6, 167-259.
  • Murray M. 1969. Structural changes in bovine ostertagiasis associated with increased permeability of the bowel wall to macromolecules. Gastroenterology, 56, 763-772.
  • Ramage J. K., Hunt R. H., Perdue M. H. 1988. Changes in intestinal permeability and epithelial differentiation during inflammation in the rat. Gut, 29, 57-61.
  • Siński E., Maclean J. M., Holmes P. H. 1987. Intestinal permeability to ⁵¹Cr-EDTA and ¹²⁵I-egg albumin in gerbils infected with Trichostrongylus colubriformis. Journal of Parasitology, 73, 423-424.
  • Watkins A. R. J., Fernando M. A. 1984. Arrested development of the rabbit stomach worm Obeliscoides cuniculi: manipulation of the ability to arrested through processes of selection. International Journal for Parasitology, 14, 559-570.

Typ dokumentu

Bibliografia

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Identyfikator YADDA

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