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2007 | 10 | 1 |

Tytuł artykułu

Peliosis hepatis-like lesion in a pekingese dog. A case report

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Warianty tytułu

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EN

Abstrakty

EN
Peliosis hepatis (PH) is a rare condition characterized by dilatation of hepatic sinusoids and the presence of blood-filled spaces within the liver. The disease occurs mainly in subjects exposed to toxic substances or estrogens, and is often asymptomatic. A 9 year-old pekingese female dog was sent to Division of Pathology for autopsy because of sudden death of unclear cause. Autopsy revealed severe hydroperitoneum (1500 ml of transsudate), dilatation of heart ventricles, passive hyperemia of lungs, spleen and kidneys. The liver was enlarged, with slightly wrinkled surface, with many red spots, of different size and shape. Microscopic examination of the liver revealed the presence of areas with severe dilatation of hepatic sinusoids, and multiple cystic spaces filled with blood. Some of these spaces were lined with endothelium and other were not. Spaces were different in shape and size and were localized in the areas between dilated sinusoids. Based on the macroscopic and microscopic examination, the liver lesions were identified as severe hepatic sinusoidal dilatation with formation of peliosis hepatis-tike structures.

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-

Rocznik

Tom

10

Numer

1

Opis fizyczny

p.43-46,fig.,ref.

Twórcy

  • Warsaw Agricultural University, Nowoursynowska 159c, 02-766 Warsaw, Poland

Bibliografia

  • Anthony PP (2003) Tumors of the hepatobiliary system. In: Fletcher DDM (ed) Diagnostic histopathology of tumors. Churchil Livingstone, New Yiork, pp 411-460.
  • Berzigotti A, Magalotti D, Zappoli P, Rossi C, Callea F, Zali M (2006) Peliosis hepatis as an early histological finding in idiopathic portal hypertension. A case report. World J Gastroenterol 12: 3612-1615.
  • Edwards R, Colombo T, Greaves P (2002) “Have you seen this?” Peliosis hepatis. Tox Pathol 30: 521-523.
  • Goodman ZD, Ishak KG (1997) Medical diseases of the liver. In: Silverberg SG (ed) Principles and practice of surgical pathology and cytopathology. vol. 2, Churchil Livingstone, New York , pp 1867-1939.
  • Kelly JP (2004) A review of bacterial pathogens in Ctenocephalides felis in New Zeland N Z Vet J 52: 352-357.
  • Lee KP (1983) Peliosis hepatis-like lesion in aging rats. Vet Pathol 20: 410-423.
  • Kitchal BE, Fan TM, Kordick D, Breitschwerdt EB, Wollen- berg G, Lichtensteiger CA (2000) Peliosis hepatis in a dog infected with Bartonella henselae. J Am Vet Med Assoc 216: 519-523.
  • Nieves CC, Solis Herruzo JA, Munoz-Yaque MT, De Bias C (1989) Hepatic peliosis. Review of the literature. Rev Esp Enferm Apar Dig 75: 205-211.
  • Onda H, Kaneda Y, Ito Y, Wakabayashi T (1982) Peliosis hepatis. A specific lesion in the bovine liver. Acta Pathol Jpn 32: 1053-1058.
  • Pappalardo BL, Brown TT, Tompkins M, Breitschwerdt EB (2001) Immunopathology of Bartonella vinsoni (berkhof- fii) in experimentally infected dogs. Vet Immunol Im- munopathol 83: 125-147.
  • Solis-Heruzzo JA, Colina F, Munoz-Yague MT, Castellano G, Marillas JD (1983) Reddish-purple areas on the liver surface: the laparoscopic pisture of peliosis hepatis. En­doscopy 15: 96-100.
  • Wakabayashi T, Onda H, Tada T, Ijjima M, Itoh Y (1984) High incidence of peliosis hepatis in autopsy cases of aplastic anemia with special reference to anabolic steroid therapy Acta Pathol Jpn 34: 1079-1086.

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Bibliografia

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