Study of bioactive compounds from Streptomyces sp. ANU 6277

• Autorzy: Narayana K J P , Prabhakar P. , Vijayalakshmi M. , Venkateswarlu Y. , Krishna P.S.J.
• Języki publikacji: EN

Abstrakty

EN

An attempt was made to study the bioactive compounds from a terrestrial Streptomyces sp. ANU 6277 isolated from laterite soil. Four active fractions were recovered from the solvent extracts obtained from the culture broth of five day-old strain. Three bioactive compounds were purified and identified as 3-phenylpropionic acid, anthracene-9,10-quinone and 8-hydroxyquinoline. The components of the partially purified fourth active fraction were analyzed by gas chromatography-mass spectrometry and identified as benzyl alcohol, phenylethyl alcohol and 2H-1, 4-benzoxazin-3 (4H)-one. Four active fractions were screened for antimicrobial activity against Gram-positive and Gram-negative bacteria, and fungi including phytopathogenic, toxigenic and dennatophytic genera. Among these metabolites, 8-hydroxyquinoline exhibited strong antibacterial and antifungal activity as compared to 3-phenylpropionic acid and anthracene-9,10-quinone.

Słowa kluczowe

EN

mass spectrometry; 8-hydroxyquinoline; bioactive compound; antimicrobial activity; anthracene-9; gas chromatography; 10-quinone; 3-phenylpropionic acid; Streptomyces

• Wydawca: -
• Czasopismo: Polish Journal of Microbiology
• Rocznik: 2008
• Tom: 57
• Numer: 1
• Opis fizyczny: p.35-39,fig.,ref.

Twórcy

autor

Narayana K J P

• Acharya Nagarjuna University, Guntur-522 510, A.P., India

autor

Prabhakar P.

autor

Vijayalakshmi M.

autor

Venkateswarlu Y.

autor

Krishna P.S.J.

Bibliografia

• Berdy J. 2005. Bioactive microbial metabolites. J. Antibiot. 58: 1-26.
• Bibb M.J. 2005. Regulation of secondary metabolism in Streptomycetes. Curr: Opin. Microbiol. 8: 208-215.
• Biswas S. 2003. 8-Hydroxyquinoline inhibits the multiplication of Plasmodium falciparum in vitro. Ann. Trop. Med. Parasitol. 97: 527-530.
• Cappuccino J.G and N. Sherman 1999. Microbiology-A Laboratory Manual (Harlow: Benjamin) pp. 263-264.
• Claeson A.S. and A.L. Sunesson. 2005. Identification using versatile sampling and analytical methods of volatile compounds from Streptomyces albidoflavus grown on four humid building materials and one synthetic medium. Indoor Air 15: 41-47.
• Clark B., R.J. Capon, M. Stewart, E. Lacey, S. Tennant and J.H. Gill. 2004. Blanchaquinone: A new anthraquinone from an Australian Streptomyces sp. J. Nat. Prod. 67: 1729-1731.
• Goto M., M.A. Masegi, T. Yamauchi, K.I. Chiba, Y. Kuboi, K. Harada and N. Naruse. 1998. K115 A, a new anthraquinone derivative that inhibits the binding of activator protein-1 (AP-1) to its recognition sites. I. Biological activities. J. Antibiot. 36: 2748-2750.
• Huang Y.F., L. Tian, H.W. Fu, H.M. Hua and Y.H. Pei. 2006. One new anthraquinone from marine Streptomyces sp. FX-58. Nat. Prod. Res. 20: 1207-1210.
• Hwang B.K., S.W. Lim, B.S. Kim, J.Y. Lee and S.S. Moon. 2001. Isolation and in vivo and in vitro antifungal activity of phenyl acetic acid and sodium phenyl acetate from Streptomyces humidus. Appl. Environ. Microbiol. 67: 3739-3745.
• Hwang S.Y., S.H. Lee, K.J. Song, Y.P. Kim and K. Kawahara. 1998. Purification and characterization of antistaphylococcal substance from Pseudomonas sp.KUH-001. J. Microbiol. Biotechnol. 8: 111-118.
• Kenawy E. 2001. Biologically active polymers. IV. Synthesis and antimicrobial activity of polymers containg 8-hydroxyquinoline moiety. J. Appl. Polymer Sci. 82: 1364-1374.
• Mack S.B. and A. Zeeck. 1987. Secondary metabolites by chemical screening I. Calcium 3-hydroxyquinoline-2-carboxylate from a Streptomyces. J. Antibiot. 40: 953-960.
• Narayana K.J.P., P. Prabhakar, M. Vijayalakshmi, Y. Vekateswarlu and P.S.J. Krishna. 2007. Biological activity of phenyl-propionic acid from a terrestrial Streptomycetes. Pol. J. Microbiol. 56: 191-197.
• Prabavathy V.R., N. Mathivanan, K. Murugesan. 2006. Control of blast and sheath blight diseases of rice using antifungal metabolites produced by Streptomyces sp. PM5. Biological Control 39 : 313-319.
• Roy R.N., S. Laskar and S.K. Sen. 2006. Dibutyl phthalate, the bioactive compound produced by Streptomyces albidoflavus 321.2. Microbiol. Res. 161: 121-126.
• Sahin N. and A. Unger. 2003. Investigation of the antimicrobial activity of some Streptomyces isolates. Turk. J. Biol. 27: 79-84.
• Sanglier J.J., E.M.H. Wellington, V. Behal, H.P. Feidler, R.E. Ghorbel, C. Finance, M. Hacene, A. Kamoun, C. Kelly, D.K. Mercer, S. Prinzis and C. Tringo. 1993. Novel bioactive compounds from actinomycetes. Res. Microbiol. 144: 661-663.
• Short B.R.D., M.A. Vargas, J.C. Thomas, S.O. Hanlon and M.C. Enright. 2006. In vitro activity of a novel compound, the metal ion chelating agent AQ⁺, against clinical isolates of Staphylococcus aureus. J. Antimicrob. Chemother. 57: 104-109.
• Sugaya K., M. Yoshida, K. Yamagiwa and A. Ohkawa. 2005. Mass production of microorganism, Comamonas sp. TKV3-2-1, for biodegradation of quinoline in crude oil. Material Technol. 23: 36-43.
• Williams ST. and T. Cross. 1971. Isolation, purification, cultivation and preservation of actinomycetes. Methods Microbiol. 4: 295-334.
• You B.Y., Y.H. Wang and M.L. Kuo. 1999. Evaluation of geno-toxicity and carcinogenicity on fungicide, copper 8-hydroxyquinolinate, by short-term tests. Zhiwu Baohu Xuchui Huikan (in Chinese) 41: 119-130.