Oral immunization of piglets with Escherichia coli vaccine. I. Serum antibodies

• Autorzy: Osek J
• Języki publikacji: EN

Abstrakty

EN

Protection of weaned piglets against E.coli diarrhea depends on specific antibacterial and/or antitoxic antibodies induced by oral immunization. A formalin-inactivated vaccine, consisting of E.coli strain O149:K91 expressing the F4ac fimbrial antigen and B subunit of CT was orally administered to 3 - 4-week-old pigs. The serum anti-LPS, anti-F4ac, and anti-CTB antibodies were tested by ELISA. It was shown that the vaccine given either in two or three doses induced a strong antibody response. The highest antibody titers against all protective antigens were found on day 21 after immunization and the specific immunoglobulins were mainly of the lgG and lgA isotypes.

Słowa kluczowe

EN

vaccine; ELISA test; oral immunization; Escherichia coli; piglet; serum antibody; immune response

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 1999
• Tom: 43
• Numer: 1
• Opis fizyczny: p.33-41

Twórcy

autor

Osek J

• National Veterinary Research Institute, 24-100 Pulawy, Poland

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