Cytoskeleton and red cell shape

• Autorzy: Svetina S. , Iglic A. , Kralj-Iglic V. , Zeks B.
• Języki publikacji: EN

Abstrakty

EN

A view is presented on different roles which the bilayer part of the membrane and the skeleton play in establishing normal and some abnormal RBC shapes. The system is first studied at the level of elastic properties of red blood cell membrane where the latter is considered to be a trilayered structure. Then the contributions to the membrane energy are introduced which cause the membrane to become laterally inhomogeneous, in particular, the skeleton-bilayer interaction, the interaction between the membrane embedded molecules and the membrane curvature, and the distributional free energy of membrane embedded molecules. It is invoked that the role of skeleton in stabilizing red blood cell membrane is in keeping membrane integral proteins laterally distributed as homogeneously as possible.

Słowa kluczowe

EN

cytoskeleton; membrane skeleton; blood cell; membrane curvature; erythrocyte; trilayer structure; membrane elasticity; skeleton; detachment; cell shape; bilayer couple model

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 1996
• Tom: 01
• Numer: 1
• Opis fizyczny: p.67-78,fig.

Twórcy

autor

Svetina S.

• University of Ljubljana, SI 61000 Ljubljana, Slovenia

autor

Iglic A.

autor

Kralj-Iglic V.

autor

Zeks B.

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