Charakterystyka molekularna genu wirusowej interleukiny 8 [vIL8] krajowych szczepow wirusa choroby Mareka

• Autorzy: Krol K , Samorek-Salamonowicz E. , Kozdrun W.

Warianty tytułu

EN

Molecular characteristics of the vIL8 gene of Polish MDV strains

• Języki publikacji: PL

Abstrakty

EN

The aim of the foregoing experiment was the determination and comparison of the nucleotide and amino acid sequences of the vIL-8 gene of Polish MDV strains. Twenty three samples isolated from field cases of Marek’s disease virus during the years 1976 2005 were used in the experiment. The presence of the gene was confirmed in all examined samples. No changes in the vIL8 sequence were stated, except of the three following strains, where singular nucleotide changes were observed: 16/05 (25 C→T; 243 C→T; 281 G→A), PZ /95 (25 C→T; 184 A→G; 243 C→T; 281G→A), 5/01 (168 C→T; 220 T→C), 11/02 (464 T→A), 23/99 (665 T→A), 14/05 (551 T→A, deletion of 680 base). These changes were reflected in amino acid sequences of the three isolates, as point and random changes: 16/05, PZ/95 (4 S→L, 31 G→D), and 14/05 (88 F→L). It appears that these changes did not show any pattern displaying association with the degree of the pathogenicity of the virus, and that the gene encoding vIL8 in most cases did not change within 30 years.

Słowa kluczowe

PL

wirusologia; wirus choroby Mareka; szczepy wirusowe; gen vIL8; charakterystyka molekularna; sekwencja nukleotydow

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2008
• Tom: 64
• Numer: 06
• Opis fizyczny: s.804-806,rys.,fot.bibliogr.

Twórcy

autor

Krol K

• Panstwowy Instytut Weterynaryjny - Panstwowy Instytut Badawczy, Al.Partyzantow 57, 24-100 Pulawy

autor

Samorek-Salamonowicz E.

autor

Kozdrun W.

Bibliografia

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