Influence of phosphorohydrazone derivatives of benzopyrones on polymerization and viscosity of fibrin

• Autorzy: Michalska M. , Pajak W. , Kolodziejska J. , Lazarenkow A. , Nawrot-Modranka J.
• Języki publikacji: EN

Abstrakty

EN

The synthesis and antitumour and antibacterial activity of coumarin and chromone phosphorohydrazones have been reported. This study describes influence of phosphorohydrazones derivatives of coumarin and chromone on the polymerization and viscosity of fibrin. The fibrin polymerization assay was performed by the Shen and Lorand method and the clot viscosity was measured on the basis of Shen and Lorand and Marchi and coworkers methods. Among the eight compounds tested, one coumarin derivative and two chromone derivatives showed significant activity

Słowa kluczowe

PL

phosphorohydrazone derivative; polymerization; viscosity; fibrin; coumarin; antitumour activity; antibacterial activity

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2008
• Tom: 55
• Numer: 3
• Opis fizyczny: p.613-617,fig.,ref.

Twórcy

autor

Michalska M.

• Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland

autor

Pajak W.

autor

Kolodziejska J.

autor

Lazarenkow A.

autor

Nawrot-Modranka J.

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