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2006 | 15 | 4 |

Tytuł artykułu

Effect of dried roots of Astragalus membranaceus in the diets of young growing pigs on growth performance and immune function

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The experiment was conducted to investigate the effect of Astragalus powder prepared by using different comminution techniques on growth performance and immune function of pigs. Duroc×Landrace×Yorkshire young growing pigs (n=90, female, 60 days of age, liveweight 21.88±1.26 kg) were randomly allocated to three treatments. Each treatment had three replicates with ten pigs per pen. The basal diets were not supplemented or supplemented (5 g/kg) with 80 mesh Astragalus (180 μm), or micron Astragalus (6.32 μm), respectively; the feeding experiment lasted 30 days. After completion of the feeding experiment, three animals from each treatment were chosen to determine the effect of Astragalus on immune function. Results showed that supplementation with micron Astragalus significantly increased (P<0.05) average daily gain (ADG), both Concanavalin (ConA) and lipopolysaccharide (LPS)-induced splenocyte and peripheral lymphocyte proliferation, and significantly increased (P<0.05) serum IgG, IgA, IL-1α and IL-2 concentrations compared with the control groups. Supplementation with 80 mesh Astragalus only increased (P<0.05) serum IgA, IL-1α and IL-2 concentrations compared with control. The results indicated that micron Astragalus was more effective than 80 mesh Astragalus in improving growth performance and enhancing immune function of pigs.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

15

Numer

4

Opis fizyczny

p.599-607,fig.,ref.

Twórcy

autor
  • Zhengzhou College of Animal Husbandry Engineering, Zhengzhou, 450008, P.R. China
autor
autor
autor
autor
autor

Bibliografia

  • Bedir E., Pugh N., Calis I., Pasco D.S., Khan I.A., 2000. Immunostimulatory effects of cycloartanetype triterpene glycosides from Astragalus species. Biol. Pharm. Bull. 23, 834-837
  • Chen H.L., Zhuo B.S., Li D.F., Chang B.Y., Zhang J.X., 2003. Effect of Astragalus on lymphocyte prolifieration and signal molecules in the spleen of broilers. Chin. J. Vet. 39, 11-14
  • Du X.M., He L., 2000. Comparision of medicinal efficiency of traditional machining and super-fine comminution treated Chinese medicine. Chin. Med. 22, 307-309
  • Erdem Y., Erdal B., Ihsan C., Yoshihisa T., Yasukazu O., 2005. Effect of triterpene saponins from Astragalus species on in vitro cytokine release. J. Ethnopharmacol. 96, 71-77
  • Hamilton-Miller M.T., 2004. Antibiotic resistance from two perspectives: man and microbe. Int. J. Antimicrobial Agents 23, 209-212
  • Hong C.Y., Ku J., Wu P., 1992. Astragalus membranaceus stimulates human sperm motility in vitro. Amer. J. Chin. Med. 20, 289-294
  • Jin R., Kurashige S., 1996. Effects of shi-ka-ron on cytokine production of lymphocytes in mice treated with cyclophosphamide. Amer. J. Chin. Med. 24, 37-44
  • Kong X.F., Hu Y.L., Rui R., 2004. Effects of Chinese herbal medicinal ingredients on peripheral lymphocyte proliferation and serum antibody titer after vaccination in chicken. Int. Immunopharmacol. 4, 975-982
  • Lee Y.S., Han O.K., Park C.W., Yang C.H., Jeon T.W., Yoo W.K., Kim S.H., Kim H.J., 2005. Pro-inflammatory cytokine gene expression and nitric oxide regulation of aqueous extracted Astragali Radix in RAW 264.7 macrophage cells. J. Ethnopharmacol. 100, 289-294
  • Li C.M., Gai G.S., He X.H., Xing D.M., 2004. Application of powder technology in Chinese traditional medicine. China Powder Technol. 3, 48-51
  • Li Z.S., Qiu S.C., Hu Y., Bai X.L., 2002. Effect of Astragalus membranaceus on lymphocyte proliferation and IL-2 production of mice. J. Binzhou Med. College 25, 446-447
  • Liu J.X., Wang C.Y., Bai Y.M., Fang Y.P., 1998. Influence of Astragalus and other nine natural medicines on Newcattle disease antibody titers(ND-HI), coefficient of the immune organs and gains of chicks. Chin. J. Vet. Sci. Technol. 12, 30-32
  • NRC, 1998. Nutrient Requirements of Swine. 10th Edition. National Academy Press. Washington, DC
  • Park J.S., Lee J.H., Ha T.Y., 2000. Effects of capsaicin pretreatment on the function of mouse peritoneal macrophages. Korean J. Immunol. 22, 39-49
  • Sheng Y., Liu C.B., Tu M.J., 2003. Applied vantage and outlook of modern production for Chinese herbal medicine using superfine communication technique. China Powder Sci. Technol. 9, 28-31
  • Song Q.H., Kobayashi T., Xiu L.M., Hong T., Cyong J.C., 2000. Effects of Astragali root and Hedysari root on the murine B and T cell differentiation. J. Ethnopharmacol. 73, 111-119
  • Sun G.C., Liu W.J., 2004. Research of the effect of the piglet dietary addition of Astragalus. Henan J. Anim. Sci. Vet. Med. 25, 8
  • Xie M.Q., Song C.X., 2000. Effects of five immune enhancers on the PBMC proliferation of swine. Chin. J. Vet. Sci. 20, 485-486
  • Xu L.J., Lu F.E., Zou X., Wei S.C., 2004. A study of the solubilization of Rhizoma Coptidis powdered to micrometer particles. Herald Med. 23, 374-375
  • Yang H.C., Zheng S.J., 1992. Experimental Techniques in Veterinary Immunology. Beijing Agricultural University Press, Beijing (China)
  • Zee-Cheng P.K., 1992. Shi-quan-da-bu-tong (ten significant tonic decoction), SQT. A potent Chinese biological response modifier in cancer immunotherapy, potentiation and detoxification of anticancer drugs. Meth. Find. Exp. Clin. Pharmacol. 14, 725-736
  • Zhao K.S., Mancini C., Doria G., 1990. Enhancement of the immune response in mice by Astragalus membranaceus extracts. Immunopharmacology 20, 225-233
  • Zhou J.Y., Wang J.Y., Chen J.G., Wu J.X., 2005. Cloning, in vitro expression and bioactivity of duck interleukin-2. Mol. Immunol. 42, 589-598
  • Zou Y.M., 2005. Comparative study on bulk density, liquidity the effective ingredient of the micro powder and fine powder of three traditional Chinese medicinal materials. Lishizhen Med. Mat. Med. Res. 16, 761-762

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-c68c1140-3dc9-409a-87f0-cb6a58b594f4
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