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2001 | 60 | 3 |

Tytuł artykułu

Contributions to the study of the foetal development of physiological intimal thickening in the human uterine artery

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The morphological study of the development of “intimal thickenings” of the human uterine artery in physiological condition was performed on 72 uterine arteries obtained from foetuses from the 12th week of gestation up to birth. Our results indicate that intimal thickening is formed by the migration and displacement of mesenchymal cells around the site of origin of collateral vessel from uterine mesothelium. These cells firstly differentiate into the myoblasts and then into the myocites. During the development the internal limitans membrane separates the intimal thickening from the tunica media and the elastic fibres appearing inside possessing a muscle-elastic nature. The function of intimal thickenings is the regulation of local blood flow by means of the control of myocitic contractile capacity; these cells play a fundamental role in endothelium-intimal smooth muscle cell contact.

Słowa kluczowe

Wydawca

-

Czasopismo

Rocznik

Tom

60

Numer

3

Opis fizyczny

p.199-203,fig.,ref.

Twórcy

autor
  • University of Zaragoza, c/ Domingo Miral, s/n, 50009 Zaragoza, Spain
autor
autor
autor
autor

Bibliografia

  • 1. American Heart Association Sac (Steering Committee) (1992) A definition of intima of human arteries and its artherosclerosis-Prone Regions. Arteriosclerosis and thrombosis. 12 (1): 120–134.
  • 2. Beny JL, Pacicca C (1994) Bidirectional electrical communication between smooth muscle and endothelial cells in the pig coronary artery. Am J Physiol, 266: 1465–1472.
  • 3. Diaz MP, Torres A, Sarrat R (1987) Cojinetes endoarteriales y organización del material elástico en las arterias genitales femeninas. Anales de Anatomía, 33: 13–19.
  • 4. Heidger PM, Van Orden DE, Farley DB (1983) Electron microscopic and histochemical characterization of intra-arterial cushions of the rat and porcine uterine vascular bed. Acta Anat, 117: 239–247.
  • 5. Kardon RH, Farley DB, Heidger PM, Van Orden DE(1982) Intra-arterial cushions of the rat uterine artery: a scanning electron microscope evaluation utilizing vascular casts. Anat Rec, 203: 19–29.
  • 6. Li DY, Brooke B, Davis EC, Mecham RP, Sorensen LK, Boak BB, Eichwald E, Keating MT (1996) Elastin is an essential determinant of arteries morphogenesis. Nature, 393: 276–280.
  • 7. Marchenko SM, Sage SO (1994) Smooth muscle cells affect endothelial membrane potential in the aorta. J Physiol, 267 (2): 804–811.
  • 8. Matonoha P, Zechmeister A (1980) Structure of the coronary arteries in the prenatal period in man. Folia Morph (Prague), 28 (3): 272–274.
  • 9. Moffat DB (1959) An intraarterial regulating mechanism in the uterine artery of the rat. Anat Rec, 134: 107–123.
  • 10. Ortiz PP, Whyte J, Diaz P, Tierz JA, Torres A, DanielLamaziere JM, Lavallee J, Sarrat R (1997) Estudio morfométrico de la arteria uterina humana. Acta Ginecológica, LIV (8): 229–236.
  • 11. Rapola J, Pesone E (1977) Coronary artery changes in newborn babies. A histological and electron microscopical study. Acta Path Microbiol Scand Sect Pathol, 85: 286–296.
  • 12. Robertson JH (1960) Stress zones in foetal arteries. J Clin Path, 13: 133–143.
  • 13. Robertson JH (1960) The significance of intimal thickening in the arteries of the newborn. Arch Dis Child, 35: 558–590.
  • 14. Sasaguri Y, Murahashi N, Sugama K, Kato S, Hiraoka K, Satoh T, Isomoto H, Morimatsu M (1994) Development-related changes in matrix metalloproteinase expression in human aortic smooth muscle cells. Lab Invest, 71 (2): 261–269.
  • 15. Slomp J, Van Munsteren JC, Poelman RE, De Reeder EG, Borgers AJ, Gittenberger De Groot AC (1992) Formation of intimal cushions in the ductus arteriosus as a model for vascular intimal thickening. An immunohistochemical study of changes in extracellular matrix components. Atherosclerosis, 93 (1): 25–39.
  • 16. Sosa-Melgarejo JA, Berry CL (1995) Myoendothelial contacts in the human fetal aorta. Arch Med Res, 26 (4): 431–435.
  • 17. Stary HC, Blankenhorn DH, Chandler AB (1992). A definition of intima of human arteries and its artherosclerosis-Prone Regions. Circulation, 85: 391–405.
  • 18. Stepanov PF, Sapozhnikov AG (1985) Age and change in the structure of the walls of the intrinsic arteries of the uterus. Arkh Anat Gistol Embriol, 88 (5): 50–57.
  • 19. Thyberg J (1998) Phenotypic modulation of smooth muscle cells during formation of neointimal thickenings following vascular injury. Histol Histopathol, 13: 871–891.
  • 20. Velican C, Velican D (1976) Intimal thickening in developing coronary arteries and its relevance to atherosclerotic involvement. Atherosclerosis, 23: 345–355.
  • 21. Whyte J, Diaz MP, Tierz JA, Pellejero S, Lostale F, Ortiz PP, Torres A, Sarrat R (1996) Engrosamientos intimales en la arteria uterina humana. Act Gin, LIII: 13–20.
  • 22. Wight TN (1996) The vascular extracellular matrix. In: Fuster V, Ross R, Topol EJ (eds.). Atherosclerosis and coronary artery disease. Lippincott-Raven-Publishers. Philadelphia, pp. 421–440.
  • 23. Zhun NL, Wu L, Liu PX, Gordon EM, Anderson F, Starnes VA, Hall FL (1997) Downregulation of cyclin G1 expression by retrovirus-mediated antisense gene transfer inhibits vascular smooth muscle cell proliferation and neointima formation. Circulation, 96: 628–635.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-c64dd645-02cf-4563-bcd0-ab221810a53d
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