Wrazliwosc na wybrane antybiotyki beta-laktamowe klinicznych szczepow Escherichia coli i Klebsiella pneumoniae

• Autorzy: Andrzejewska E. , Szkaradkiewicz A. , Kaniasty M.
• Języki publikacji: PL

Abstrakty

PL

W pracy dokonano analizy lekooporności szczepów Escherichia coli i Klebsiella pneumoniae izolowanych od pacjentów. Wykonano testy określające zdolność bakterii do produkcji ß-laktamaz o rozszerzonym spektrum substratowym (ESBL).

EN

The studies aimed at analysing the resistance to some ß-lactam antibiotics among E. coli and K. pneumoniae clinical isolates and at evaluating. The extended spectrum of ß-lactamases (ESBL) production in the isolates. The analysis included 137 E. coli strains and 52 K. pneumoniae strains, isolated from hospitalized patients and out-patients treated in the first trimester of 1998. The strains were identified using the ATB computer system. Antibiotic sensitivity of the isolates was determined by disc-diffusion tests. ESBL production capacity of E. coli and K. pneumoniae strains was estimated by double-disc and ATB BLSA tests. Most of the analysed E. coli strains were found to exhibit significant sensitivity to compound penicillin preparations containing ß-lactarn inhibitor (Augmentin, Tazocin) and to the third generation cefalosporins, in contrast, K. pneumoniae strains much more frequently were resistant to the drugs. Among the obtained isolates, 3 (2,2%) E. coli strains and 21 (40,4%) K. pneumoniae strains produced ESBL but all the isolates proved sensitive to imipenem. In evaluation of ESBL production-detecting tests, the double-disc test was found to be more reliable than ATB BLSA test.

Słowa kluczowe

PL

szczepy bakteryjne; Escherichia coli; antybiotyki beta-laktamowe; wrazliwosc na antybiotyki; Klebsiella pneumoniae

• Wydawca: -
• Czasopismo: Medycyna Doświadczalna i Mikrobiologia
• Rocznik: 1998
• Tom: 50
• Numer: 3-4
• Opis fizyczny: s.197-205,fot.,tab.,bibliogr.

Twórcy

autor

Andrzejewska E.

• Akademia Medyczna, 61-712 Poznan, ul.Wieniawskiego 3

autor

Szkaradkiewicz A.

autor

Kaniasty M.

Bibliografia

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