Oxidant defence enzymes in different isolates of Trichinella

• Autorzy: Hadas E , Rodriguez-Caabeiro F , Gonzales A J
• Języki publikacji: EN

Abstrakty

EN

The prevention of biological damage brought about by free radical mediated mechanisms can be achieved by specific chemical scavengers which trap free radicals as well as by protective enzymes that remove hydrogen peroxide or superoxide radicals. The aim of this study was to carry out a comparative analysis of enzymes acting against free-radicals and peroxides in Trichinella spiralis, T. nelsoni and T. pseudospiralis isolates. The activity of superoxide dismutase in T. pseudospiralis was about two times higher than in T. spiralis and about 1.5 times higher than that of T. nelsoni. In all the isolates only one band representing superoxide dismutase was identified on electrophoretic analysis. Catalase and peroxidase activities were very low. Using electrophoretical analysis we found three identical bands of peroxidase activity in the species investigated. Our data suggest that, with regard to the anti-oxidant enzymes, superoxide dismutase plays an important role whereas peroxidase and catalase play lesser roles in the defence of Trichinella spp. larvae against host generated free radicals released during the response to infection.

Słowa kluczowe

EN

protective enzyme; Trichinella; peroxide; free radical

• Wydawca: -
• Czasopismo: Acta Parasitologica
• Rocznik: 1994
• Tom: 39
• Numer: 1
• Opis fizyczny: p.32-36,fig.

Twórcy

autor

Hadas E

• Department of Biology and Medical Parasitology, K.Marcinkowski Academy of Medical Sciences, Poznan, Poland

autor

Rodriguez-Caabeiro F

• Department of Microbiology and Parasitology, Faculty of Pharmacy, University of Alcala de Henares, Madrid, Spain

autor

Gonzales A J

• Department of Microbiology and Parasitology, Faculty of Pharmacy, University of Alcala de Henares, Madrid, Spain

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