Ethyl [1S, 2RS]-and [1S,2S]-2-[2-chloro-propanoyloxy]propanoate. Preparation and hydrolysis

• Autorzy: Polec I. , Komorowska-Kulik J. , Kielczewska A. , Bombinska D. , Legocki J.
• Języki publikacji: EN

Abstrakty

EN

Ethyl (1S,2RS)-2-(2-chloropropanoyloxy)propanoate ((1S,2RS)-(I)) was obtained from rac-2-chloropropionyl chloride and ethyl L-lactate. (1S,2S)- (I) was also synthesized from (S)-2-chloropropionyl chloride and ethyl L-lactate with 93% d.e. (I) was undertaken hydrolysis by different media: NaOH/THF-H2O, Na2CO3/THF-H2O, LiOHxH2O/THF-H2O, 25% NaOH/H2O, and weakly acidic ion-exchange resin Amberlite IRC748 dispersion in MeOH. (1S,2RS)-2-(2-Chloropropanoyloxy) propanoic acid (II) diastereomers were identified as products of acidic hydrolysis with the ionic resin. GC/MS, HPLC and HPLC/MS analyses of resulted products are presented.

Słowa kluczowe

EN

ethyl 2-[2-chloro-propanoyloxy]propanoate; hydrolysis; ethyl L-lactate; 2-chloropropionyl chloride

• Wydawca: -
• Czasopismo: Pestycydy
• Rocznik: 2008
• Numer: 3-4
• Opis fizyczny: p.27-52,fig.,ref.

Twórcy

autor

Polec I.

• Institute of Industrial Organic Chemistry, 6 Annapol St., 03-236 Warsaw, Poland

autor

Komorowska-Kulik J.

autor

Kielczewska A.

autor

Bombinska D.

autor

Legocki J.

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