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2009 | 12 | 2 |

Tytuł artykułu

Lymphadenomegaly in dogs - cytological study

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Lymphadenomegaly is the enlargement of the lymph node/nodes, due to various nonneoplastic or neoplastic processes, observed mainly in dogs, rarely in other animal species. The first step of a diagnostic procedure in cases of lymph nodes enlargement, apart from physical examination and morphological blood analysis, should be a cytological examination of an enlarged lymph node/nodes. The aim of the present study was to determine the character and the cause of the lymph node/nodes enlargement in dogs and to evaluate the usefulness of fine-needle cytology in a diagnosis of lymphadenomegaly. The study was performed on dogs submitted to consultation in the Small Animal Clinic of Department of Clinical Sciences, Warsaw University of Life Sciences, due to generalized or local lymphadenomegaly, and in which fine-needle biopsy was made. A signalement, general state of dog, the presence and duration of clinical signs, the character (generalized vs. localized) and intensity (mild, moderate or severe) of lympadenomegaly were recorded during physical examination. The average age of dogs examined was 8 years, 64 were males and 36 were females of various breeds; however the majority of them were greater than 25 kg in weight. The cytological diagnosis including most often lymphoma and reactive hyperplasia, more seldom metastatic neoplasm and lymphadenitis were recognized, some of the samples were considered nondiagnostic/nondefined. On the basis of the present results it can be concluded that cytological examination of good quality samples allows to obtain final diagnosis in over 90% of lymphadenomegaly. Higher incidence of canine lymphomas in males is suggested.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

12

Numer

2

Opis fizyczny

p.263-268,fig.,ref.

Twórcy

  • Warsaw University of Life Sciences, Nowoursynowska 159c, 02-766 Warsaw, Poland
autor

Bibliografia

  • Bauer NB, Zervos D, Moritz A (2007) Argyrophilic nucleo­lar organizing regions and Ki67 equally reflect prolifer­ation in fine needle aspirates of normal, hyperplastic, in­flamed, and neoplastic canine lymph nodes (n=101). J Vet Intern Med 21: 928-935.
  • Cowell RL, Dorsey KE, Meinkoth JH (2003) Lymph node cytology. Vet Clin North Am 33: 47-68.
  • Dobson JM, Blackwood LB, Mclnnes EF, Bostock DE, Nicholls P, Tom BDM (2001) Prognostic variables in ca­nine multicentric lymphosarcoma. J Small Anim Pract 42: 377-384.
  • Fournel-Fleury C, Magnol JP, Bricaire P, Marchal T, Chabanne L, Delverdier A, Bryon PA, Felman P (1997) Cytohistological and immunological classification of ca­nine malignant lymphomas: comparison with human non-Hodgkin’s lymphomas. J Comp Pathol 117: 35-59.
  • Jacobs RM, Messick JB, Valli VE (2002) Tumors of the hemolymphatic system. In: Meuten DJ (ed) Tumors in Domestic Animals. Iowa State Press, Iowa, pp 119-198.
  • Jagielski D, Lechowski R, Hoffman-Jagielska M, Winiarczyk S (2002) A retrospective study of the incidence and prog­nostic factors of multicentric lymphoma in dogs (1998-2000). J Vet Med A 49: 419-424.
  • Kiupel M, Teske E, Bostock D (1999) Prognostic factors for treated canine malignant lymphoma. Vet Pathol 36: 392- -300.
  • Sokołowska J (2004) Patomorphology of canine lymphoma. Doctoral thesis, Warsaw, Poland.
  • Thamm DH, Vail DM (2001) Mast cell tumors. In: Withrow SJ, MacEwen EG (eds) Small animal clinical oncology. Saunders Company, Phildelphia, pp 261-282.
  • Taylor JA, Baker R (2000) The lymphatic system - lymph nodes, spleen, and thymus. In: Baker R, Lumsden JH (eds) Color atlas of cytology of the dog and cat. Mosby, St. Louis, pp 71-94.
  • Teske E, van Heerde P, Rutteman GR, Kurzman ID, Moore PF, MacEwen EG (1994) Prognostic factors for treat­ment of malignant lymphoma in dogs. J Am Vet Med Assoc 205: 1722-1728.
  • Vali DM, MacEwen EG, Young KM (2001) Canine lym­phoma and lymphoid leukemias. In: Withrow SJ, Mac­Ewen EG (eds) Small animal clinical oncology. Saunders Company, Phildelphia, pp 558-590.
  • Williams LE, Tcheng Broussard M, Johnson JL, Neel J (2005) Comparsion of resutls of clinicians’ assessments, cytologic examination of fine-needle lymph node aspira­tes, and flow cytometry for detection of remission status of lymphoma in dogs. J Am Vet Med Assoc 226: 562-566.

Typ dokumentu

Bibliografia

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