Cholinergic innervation and calretinin-immunoreactive neurones in the hippocampus during postnatal development of the rat brain

• Autorzy: Ludkiewicz B , Wojcik S. , Spodnik E. , Domaradzka-Pytel B. , Morys J.
• Języki publikacji: EN

Abstrakty

EN

Immunohistochemical study of the cholinergic innervation of the hippocampal calretinin-containing cells was conducted on 28 rat brains of postnatal ages: P0, P4, P7, P14, P21, P30 and P60. Sections with double immunostaining for vesicular acetylcholine transporter (VAChT; the marker of cholinergic cells, fibres and terminals) and calretinin were analysed using confocal laser-scanning microscope. Obtained data demonstrate that during development as well as in adult species calretinin-containing neurones in the rat hippocampus form sparse synaptic contact with VAChT-ir terminals. It seems probable that cholinergic innervation is not crucial for the functioning of CR-ir cells — probably they remain under the greater influence of a system other than the cholinergic system.

Słowa kluczowe

EN

hippocampus; development; calretinin; cholinergic system; innervation; neuron; rat; brain; postnatal development

• Wydawca: -
• Czasopismo: Folia Morphologica
• Rocznik: 2002
• Tom: 61
• Numer: 1
• Opis fizyczny: p.7-14,fig.,ref.

Twórcy

autor

Ludkiewicz B

• Medical University of Gdansk, Debinki 1, 80-211 Gdansk, Poland

autor

Wojcik S.

autor

Spodnik E.

autor

Domaradzka-Pytel B.

autor

Morys J.

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