Effects of hypertonic solution administration, followed by administration of an isotonic solution, on blood parameters in sheep

• Autorzy: Bieniek K
• Języki publikacji: EN

Abstrakty

EN

The effects of iv infusion of 7.2% NaCl (HSS, 4 ml/kg; n=6) or 7.2% NaCl in 6% dextran 70 (HSD, 4 ml/kg; n=6) followed by administration of 0.9% NaCl (ISS, 32 ml/kg) on sodium (Na), chloride (Cl), potassium (K) serum concentrations, osmolality (Osm), total protein content (TP), packed cell volume (PCV), haemoglobin concentration (Hb) and red blood cell count (RBC) were evaluated in twelve healthy sheep for 360 min. The changes in blood parametres after infusion of hypertonic and isotonic solutions were not significantly different between HSS and HSD groups. In these groups the increase in Na, Cl and Osm accompanied by the decrease in K, TP, PCV, Hb and RBC were observed at 5 min after administration of hypertonic solutions. Infusion of ISS 60 min after administration of HSS or HSD did not produce a further increase in Na, Cl and Osm, whereas K, TP, PCV, Hb and RBC decreased to the lowest values at 90 min. These results indicate that the initial bolus dose of HSS or HSD produces a rapid recruitment of extravascular fluids into the vascular compartment, whereas subsequent large volume infusion of ISS maintains intravascular blood volume expansion and does not create a risk of hypernatremia.

Słowa kluczowe

EN

isotonic saline solution; sheep; hypertonic saline-dextran solution; hypertonic saline solution; blood parameter; rehydration

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 1999
• Tom: 43
• Numer: 2
• Opis fizyczny: p.167-175

Twórcy

autor

Bieniek K

• National Veterinary Research Institute, 24-100 Pulawy, Poland

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