Inhibition of tumor growth by interleukin 10 gene transfer in B16[F10] melanoma cells

• Autorzy: Walos S. , Szary J. , Szala S.
• Języki publikacji: EN

Abstrakty

EN

Interleukin 10 (IL-10) is a potent immunosuppressive cytokine with an antitumor activity. The effect of IL-10 on tumor growth was tested in murine melanoma cells manipulated by gene transfer to secrete IL-10. In mice bearing B16(F10) tumors expressing IL-10 tumor growth was decreased depending on the amount of secreted IL-10.

Słowa kluczowe

EN

mouse; mice; gene transfer; immunosuppressive cytokine; interleukin 10; melanoma cell; murine melanoma; antitumour activity; tumour growth

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 1999
• Tom: 46
• Numer: 4
• Opis fizyczny: p.967-970,fig.

Twórcy

autor

Walos S.

• Center of Oncology-Maria Sklodowska-Curie Memorial Institute, Wybrzeze Armii Krajowej, 44-101 Gliwice, Poland

autor

Szary J.

autor

Szala S.

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