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2001 | 45 | 1 |

Tytuł artykułu

Distribution of selenium in rats after repeated administration of sodium selenite

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The experiment involved Wistar rats given orally trace daily doses of selenium-75 for four weeks. The distribution of selenium-75 was evaluated in the carcass and selected organs within 28 days after the last administration. The results were compared with those reported in the literature; the kinetic data provided evidence that the absorption and distribution of selenium depend on several factors involving dosage and the route and period of administration.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

45

Numer

1

Opis fizyczny

p.63-66

Twórcy

autor
  • National Veterinary Research Institute, 24-100 Pulawy, Poland
autor

Bibliografia

  • 1. Bopp B.A., Sonders R.C., Kesterson J.W.: Metabolic fate of selected selenium compounds in laboratory animals and man. Drug Met. Rev., 1982, 13, 271-318
  • 2. Ewan R.C., Pope A.L., Baumann C.A.: Elimination of fixed selenium by the rat. J. Nutr., 1967, 91, 547-554.
  • 3. Grosicki A., Kossakowski S.: Distribution and the whole-body retention of selenium in rats treated repeatedly with inorganic mercury. Bull. Vet. Inst. Pulawy, 1992, 37, 42-47.
  • 4. Grosicki A., Kowalski B., Rachubik J.: Absorption and distribution of inorganic mercury in rats fed a copper-supplemented diet. Bull. vet. Inst. Pulawy, 1997, 41, 149-156.
  • 5. McConnell K.P.: Distribution and excretion studies in the rat after a single subtoxic subcutaneous injection of sodium selenate containing radioselenium. J. Biol. Chem., 1941, 141, 427-437.
  • 6. McKinney J. Metals bioavailability and disposition kinetics research needs workshop. Toxicol. Env. Chem., 1993, 38, 68-71.
  • 7. Shamberger R. Biochemistry of selenium. Ed. E. Frieden. Plenum Press, London 1983.
  • 8. Styblo M., Kalouskova J., Klas J.: Comparison of the kinetics of a trace and a sublethal dose of selenite in rats with particular attention being given to blood selenium distribution. J. Trace Elem. Electrolytes Health Dis., 1991, 5, 155-16.

Typ dokumentu

Bibliografia

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