Incidence of extended-spectrum beta-lactamases in clinical isolates of the family Enterobacteriaceae in a pediatric hospital

• Autorzy: Radosz-Komoniewska H , Gniadkowski M. , Rogala-Zawada D. , Nowakowska M. , Rudy M. , Wiechula B. , Martirosian G.
• Języki publikacji: EN

Abstrakty

EN

The incidence of extended-spectrum β-lactamases (ESBLs) was analyzed in Enterobacteriaceae population circulating in the Upper Silesian Child and Mother Health Center in Katowice (USC&MHC). Altogether 1164 clinical specimens, collected from children hospitalized in 8 different hospital units of USC&MHC were investigated. Five hundred and eighty-five clinical isolates of the family Enterobacteriaceae were identified in specimens collected from 403 patients. Two hundred and twenty-nine Enterobacteriaceae strains (39%) isolated from 162 patients were found to be putative ESBL producers as revealed by double-disc synergy (DDS) test. ESBL activity was the most prevalent in the population of Klebsiella pneumoniae (77%), followed by Klebsiella oxytoca (50%), Serratia marcescens (43%), Escherichia coli (30%), Enterobacter spp. (18%) and Proteus mirabilis (12%). ESBL producers demonstrated also wide resistance to the non-β-lactam antimicrobial co-trimoxazole (93%) and the aminoglycosides netilmicin (88%), gentamicin (84%) and amikacin (79%).

Słowa kluczowe

EN

Enterobacteriaceae; infection; epidemiology; Enterobacter; Upper Silesian region; Proteus mirabilis; human disease; beta-lactamase; pediatric hospital; child; bacteria; Klebsiella pneumoniae; Escherichia coli; extended-spectrum beta-lactamase; Serratia marcescens

• Wydawca: -
• Czasopismo: Polish Journal of Microbiology
• Rocznik: 2004
• Tom: 53
• Numer: 1
• Opis fizyczny: p.27-34,ref.

Twórcy

autor

Radosz-Komoniewska H

• Medical University of Silesia, Medykow 18, 40-752 Katowice, Poland

autor

Gniadkowski M.

autor

Rogala-Zawada D.

autor

Nowakowska M.

autor

Rudy M.

autor

Wiechula B.

autor

Martirosian G.

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