Association between the growth hormone combined genotypes and dairy traits in Polish Black-and-White cows

• Autorzy: Dybus A , Grzesiak W. , Szatkowska I. , Blaszczyk P.
• Języki publikacji: EN

Abstrakty

EN

Associations were analysed between the bovine growth hormone combined genotypes (GH/AluI-MspI) and milk production traits in a total of 900 Polish Black-and-White (Polish Friesian) cows. PCR-RFLP method was used for genotyping. The following were frequencies of GH/AluI-MspI: 0.463 LL/++, 0.276 LV/++, 0.157 LL/+-, 0.059 LV/+-, 0.025 VV/++, 0.019 LL/-- and 0.001 (only 1 observation) of VV/+-.Significant differences were found in analysed dairy traits between cows of different GH/AluI-MspI combined genotypes. It is difficult, however, to trace a defined trend in all lactations, what to some extent complicates the inference. It is concluded that introducing the information on GH/AluI-MspI into dairy cattle marker-assisted selection (MAS) programmes would be risky.

PL

Analizowano zależności między „kombinowanymi” genotypami (combined genotypes) hormonu wzrostu (GH/AluI-MspI) a cechami użytkowości mlecznej krów rasy cb. Badaniami objęto 900 krów, o różnym udziale genów rasy hf. Dla ustalenia genotypów krów zastosowano metodę PCR-RFLP. Stwierdzono następujące frekwencje genotypów: 0,463 LL/++, 0,276 LV/++, 0,157 LL/+-, 0,059 LV/+-, 0,025 VV/++,0,019 LL/-- i 0,001 VV/+-. Wykazano istotne różnice w poziomie badanych cech zależnie od „kombinowanego” genotypu GH/AluI-MspI. Trudno jednak o wskazanie jednakowego trendu we wszystkich laktacjach, co znacznie komplikuje wnioskowanie. Wprowadzanie do programów selekcyjnych bydła mlecznego informacji o genotypie GH/AluI-MspI wydaje się ryzykowne.

Słowa kluczowe

EN

cow; cattle; genotype; animal breeding; growth hormone; polymerase chain reaction; Black-and-White breed; RFLP method

• Wydawca: -
• Czasopismo: Animal Science Papers and Reports
• Rocznik: 2004
• Tom: 22
• Numer: 2
• Opis fizyczny: p.185-194,ref.

Twórcy

autor

Dybus A

• Agricultural University, Doktora Judyma 12, 71-460 Szczecin, Poland

autor

Grzesiak W.

autor

Szatkowska I.

autor

Blaszczyk P.

Bibliografia

• 1. ABDEL-MEGUID S.S., SHIEH H.S., SMITH W.W., DAYRINGER H.E., VIOLAND B.N., BENTLE B.A., 1987 – Three-dimensional structure of a genetically engineered variant of porcine growth hormone. Proceedings of the National Academy of Sciences, USA 84, 6434-6437.
• 2. ASTON R., RATHJEN D.A., HOLDER A.T., BENDER V., TRIGG T.E., COWAN K., EDWARDS J.S., COWDEN W.B., 1991 – Antigenic structure of bovine growth hormone: Location of a growth enhancing region. Molecular Immunology 28, 41-45.
• 3. BECKMANN J.S., SOLLER M., 1983 – Restriction fragment length polymorphisms in genetic improvement: methodologies, mapping and costs. Theoretical and Applied Genetics 67, 35-43.
• 4. CHOU K.C., ZHENG C., 1992 – Strong electrostatic loop-helix interaction in bundle motif protein structures. Biophysical Journal 63, 682-688.
• 5. COWAN C.M., DENTINE M.R., AX R.L., SCHULER L.A., 1989 – Restriction fragment length polymorphism associated with growth hormone and prolactin genes in Holstein bulls: evidence for a novel growth hormone allele. Animal Genetics 20, 157-165.
• 6. DE VOS A.M., ULTSCH M., KOSSIAKOFF A.A., 1993 – Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science 255, 306-311.
• 7. EPPARD P.J., BENTLE L.A., VIOLAND B.N., GANGULI S., HINTZ R.L., KUNG L. JR, KRIVI G.G., LANZA G.M., 1992 – Comparison of the galactopoietic response to pituitary-derived and recombinant-derived variants of bovine growth hormone. Journal of Endocrinology 132, 47-56.
• 8. FALAKI M., GENGLER N., SNEYERS M., PRANDI A., MASSART S., FORMIGONI A.,BURNY A., PORTETELLE D., RENAVILLE R., 1996 – Relationships of polymorphism for growth hormone and growth hormone receptor genes with milk production traits for Italia Holstein-Friesian bulls. Journal of Dairy Science 79, 1446-1453.
• 9. GORDON D.F., QUICK D.P., EWIN C.R., DONELSON J.E., MAURER R.A., 1983 – Nucleotide sequence of the bovine growth hormone chromosomal gene. Molecular and Cellular Endocrinology 33, 81-95.
• 10. HEDIGER R., JOHNSON S.E., BARENDSE W., DRINKWATER R.D., MOORE S.S., HETZEL J., 1990 – Assignment of the growth hormone gene locus to 19q26-qter in cattle and to 11q25-qter In sheep by in situ hybridization.Genomics 8, 171-174.
• 11. HILBERT P., MARCOTTE A., SCHWERS A., HANSET R., VASSART G., GEORGES M., 1989 – Analysis of genetic variation in the Belgian Blue Cattle breed using DNA sequence polymorphism at the growth hormone, low density lipoprotein receptor, á-subunit of glycoprotein hormones and thyroglobin loci. Animal Genetics 20, 383-394.
• 12. HOJ S., FREDHOLM M., LARSEN N.J., NIELSEN V.H., 1993 – Growth hormone gene polymorphism associated with selection for milk fat production in lines of cattle.Animal Genetics 24,91-96.
• 13. LAGZIEL A., LIPKIN E., SOLLER M., 1996 – Association between SSCP haplotypes at the bosine growth hormone gene and milk protein percentage. Genetics 142, 945-951.
• 14. LAGZIEL A., LIPKIN E., EZRA E., SOLLER M., WELLER J.I., 1999 – An MspI polymorphism at the bovine growth hormone (bGH) gene is linked to a locus affecting milk protein percentage.Animal Genetics 30, 296-299.
• 15. LEE B.K., LIN G.F., CROOKER B.A., MURTAUGH M.P., HANSEN L.B., CHESTER-JONES H., 1993 – Association of somatotropin (bST) gene polymorphism with selection for milk yield In Holstein cows. Journal of Dairy Science 76, 149.
• 16. LEE B.K., LIN G.F., CROOKER B.A., MURTAUGH M.P., HANSEN L.B., CHESTER-JONES H., 1996 – Association of somatotropin (bST) gene polymorphism at the 5th exon with selection for milk yield in Holstein cows. Domestic Animal Endocrinology 13, 373-381.
• 17. LINGAPPA V.R., DEVILLERS-THIERY A., BLOBEL G., 1977 – Nascent prehormones are intermediates in the biosynthesis of authentic bovine pituitary growth hormone and prolactin. Proceedings of the National Academy of Sciences, USA 74, 2432-2436.
• 18. LUCY M.C., HAUSER S.D., EPPARD P.J., KRIVI G.G., CLARK J.H., BAUMAN D.E., COLLIER R.J., 1993 – Variants of somatotropin in cattle: Gene frequencies in major dairy breeds and associated milk production. Domestic Animal Endocrinology 10, 325-333.
• 19. LUCY M.C., HAUSER S.D., EPPARD P.J., KRIVI G.G., COLLIER R.J., 1991 – Genetic polymorphism within the bovine somatotropin (bST) gene detected by polymerase chain reaction and endonuclease digestion.Journal of Dairy Science 74 (Suppl. 1), 284.
• 20. MITRA A., SCHLEE P., BALAKRISHNAN C.R., PIRCHNER F., 1995 – Polymorphisms at growthhormone and prolactin loci in Indian cattle and buffalo. Journal of Animal Breeding and Genetics 112, 71-74.
• 21. SABOUR M.P., LIN C.Y., SMITH C., 1997 – Association of genetic variants of bovine growth hormone with milk production traits in Holstein cattle. Journal of Animal Breeding and Genetics 114, 435-442.
• 22. SCHLEE P., GRAML R., ROTTMANN O., PIRCHNER F., 1994 – Influence of growth-hormone genotypes on breeding values of Simmental bulls. Journal of Animal Breeding and Genetics 111,253-256.
• 23. SEAVEY B.K., SINGH R.N.P., LEWIS U.J., GESCHWIND I.I., 1971 – Bovine growth hormone:evidence for two allelic forms. Biochemical and Biophysical Research Communications 43, 189-195.
• 24. WALLIS M., 1973 – The primary structure of bovine growth hormone. Federation of European Biochemical Societies Letters 35, 11-14.
• 25. WOOD D.C., SALSGIVER W.J., KASSER T.R., LANGE G.W., ROWALD E., VIOLAND B.N.,JOHNSON A., LEIMGRUBER R.M., PARR G.R., SIEGEL N.R., KIMACK N.M., SMITH C.E.,ZOBEL J.F., GANGULI S.M., GARBOW J.R., BILD G., KRIVI G.G., 1989 – Purification and characterization of pituitary bovine somatotropin. Journal of Biological Chemistry 264, 14741-14747.
• 26. WOYCHICK R.P., CAMPER S.A., LYONS R.H., HOROWITS S., GOODWIN E.C., ROTTMAN F.M., 1982 – Cloning and nucleotide sequencing of the bovine growth hormone gene. Nucleic Acid Research 10, 7197-7210.
• 27. YAO J., AGGEREY S.E., ZADWORNY D., HAYES J.F., KUHNLEIN U., 1996 – Sequence variations in the bovine growth hormone gene characterized by single-strand conformation polymorphism (SSCP) analysis and their association with milk production traits in Holsteins. Genetics 144, 1809-1816.
• 28. ZHANG H.M., MADDOCK K.C., BROWN D.R., DENISE S.K., AX R.L., 1993 – A novel allele of the bovine somatotropin gene detected by PCR-RFLP analysis. Journal of Animal Science 71, 2276.
• 29. ZWIERZCHOWSKI L., KRZYŻEWSKI J., STRZAŁKOWSKA N., SIADKOWSKA E., RYNIEWICZ Z., 2002 – Effects of polymorphism of growth hormone (GH), Pit-1, and leptin (LEP) genes,cow’s age, lactation stage and somatic cell count on milk yield and composition of Polish Black-and-White cows. Animal Science Papers and Reports 20, 213-227.