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2003 | 08 | 3 |

Tytuł artykułu

The histology of pigmented Bomirski melanoma growing in the hamster eye - preliminary results

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
We demonstrated that a quickly growing hamster skin melanoma developed a tumor after autologous implantation into the anterior chamber of the eye. Tumor cells were seen invading all the surrounding tissues, including the iris, ciliary body, choroid and cornea. Histological examination confirmed the presence of numerous blood vessels of large diameter. Their walls were very thin, thus only the endothelium could be identified using light microscopy. Macrophages, microemboli and extravasations were present within the tumor mass.

Wydawca

-

Rocznik

Tom

08

Numer

3

Opis fizyczny

p.849-856,fig.

Twórcy

  • Collegium Medicum, Jagiellonian University, Gronostajowa 7, 30-387 Krakow, Poland
autor
autor
autor

Bibliografia

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  • 2.Romanowska, B., Kukiełczak, B., Bryk, J., Mirkiewicz-Sieradzka, B., Heitzmann, J. and Łukiewicz, S. New technique for implanting Bomirski melanoma into the anterior chamber of Syrian hamster eyes. Klin. Oczna. 97 (1995) 324-327.
  • 3.Dithmar, S., Rusciano, D. and Grossniklaus, H.E. A new technique for implantation of tissue culture melanoma cells in a murine model of metastatic ocular melanoma. Melanoma Res. 10 (2000) 2-8.
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  • 6.Radnot, M. and Antal, M. Vessels of intraocular malignant melanomas. Am. J. Ophthal. 88 (1979) 472-478.
  • 7.Romanowska, B. Studies on vasculature of hamster melanoma growing in the eye. Ophthalmic Res. 30 (1998) 55.
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  • 9.Romanowska-Dixon, B., Urbanska, K., Elas, M., Pajak, S., Zygulska-Mach, H. and Miodonski, A. Angiomorphology of the pigmented Bomirski melanoma growing in hamster eye. Ann. Anat. 183 (2001) 559-565.
  • 10.Roberts, W.G. and Palade, G.E. Neovasculature induced by vascular endothelial growth factor is fenestrated. Cancer Res. 57 (1997) 765-772.
  • 11.Roberts, W.G. and Palade, G.E. Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor. J. Cell Sci. 108 (1995) 2369-2379.
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  • 13.Folberg, R., Pe'er, J., Gruman, L.M., Woolson, R.F., Jeng, G., Montague, P. R., Moninger, T.O., Yi, H. and Moore, K.C. The morphologic characteristics of tumor blood vessels as a marker of tumor progression in primary human uveal melanoma: A matched case-control study. Hum. Pathol. 23 (1992) 1298-1305.
  • 14. Li, C.Y., Shan, S., Huang, Q., Braun, R.D., Lanzen, J., Hu, K., Lin, P. and Dewhirst, M.W. Initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent models. J. Natl. Cancer Inst. 92 (2000) 143-147.
  • 15. Miodonski, A., Hodder, K. and Bakker, C. Rasterelektronenmikroskopie von Palstic-Korrosions-Preparaten: morphologishe Unterschiede zwischen Arterien und Venen. Beitr Elektronmikroskop Direkt Abbild Oberftl (BEDO, Munster) 9 (1976) 435-442.
  • 16. Ijland, S.A., Jager, M.J., Heijdra, B.M., Westphal, J.R. and Peek, R. Expression of angiogenic and immunosuppressive factors by uveal melanoma cell lines. Melanoma Res. 9 (1999) 445-450.
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  • 18. Walmsey, J. Interpretation of endothelial structure related to tumor and atherosclerotic blood vessels, in: Scanning Electron Microscopy of Vascular Casts: Methods and Applications (Motta, P.M.M., Fujita, H, Eds.) Kluwer Acad Publ Inc, 1992, 363-379.
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  • 22. McDonald, D.M. and Foss, AJ. Endothelial cells of tumor vessels: Abnormal but not absent. Cancer Metastasis Rev. 19 (2000) 109-120.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-a27c0018-2968-4a3e-8a5c-a7f08e356843
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