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Czasopismo

1998 | 43 | 3 |

Tytuł artykułu

The isolation and identification of prostaglandins of Trichostrongylus colubriformis and Haemonchus contortus

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Prostaglandins (PGs) have been implicated as precursors of biological processes, many of which are functional in parasite-host interactions. The aim of the study was the isolation and examination of PGs in extracts from adults, larvae and excretory/secretory products (E/S) of Trichostrongylus colubriformis and Haemonchus contortus. Thin-layer chromatographic (TLC) and high performance liquid chromatographic (HPLC) methods established the presence of PGs in the extracts that were identified as PGA₂, PGB₂, PGD₂, POE₂, PGF₁α, PGF₂α, PGI₂ and non-identified forms of PGs, precursors or metabolites of PGs. The qualification/quantitative profiles for the PGs were very similar for adult, L3 and E/S products of T. colubriformis and H. contortus.

Wydawca

-

Czasopismo

Rocznik

Tom

43

Numer

3

Opis fizyczny

p.167-170

Twórcy

autor
  • Department of Biology and Medical Parasitology, K.Marcinkowski University of Medical Sciences, Fredry 10, 61-701 Poznan, Poland
autor
  • AgResearch, Wallaceville Animal Research Centre, P.O. Box 40063, Upper Hutt, New Zealand
  • AgResearch, Wallaceville Animal Research Centre, P.O. Box 40063, Upper Hutt, New Zealand

Bibliografia

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  • Decker K. 1985. Eicosanoids, signal molecules of liver cells. Seminar in Liver Disease, 5, 175-190.
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  • Frandsen J. C., Bone L. W. 1989. Prostanoids of nematodes: prostaglandins and thromboxane B₂ from Trichostrongylus colubriformis and Turbatrix aceti. Comparative Biochemistry and Physiology, 92C, 185-187.
  • Frayha G. J., Smyth J. D. 1983. Lipid metabolism in parasitic helminths. Advances in Parasitology, 22, 309-387.
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  • Fusco A. C., Salafsky B., Shibuya T. 1993. Cytokine and eicosanoid regulation by Schistosoma mansoni during LSE penetration. Mediators of Inflammation, 2, 73-77.
  • Goldings E. A. 1986. Regulation of B cell tolerance by macrophage-derived mediators: antagonistic effects of prostaglandin E₂ and interleukin 1. Journal of Immunology, 136, 817-820.
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  • Hadaś E., Mazur T. 1997. Biosynthesis of prostaglandins in pathogenic and non-pathogenic strains of Acanthamoeba spp. Parasitology Research, 83, 296-299.
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  • Pilet C. (Ed.) 1985. Special issue on macrophages. Comparative Immunology, Microbiology and Infectious Diseases, 8, 73- 224.
  • Salafsky B., Fusco A. C. 1985. Schistosoma mansoni: cercarial eicosanoid production and penetration response inhibited by esculetin and ibuprofen. Experimental Parasitology, 60, 73-81.
  • Salafsky B., Fusco A. C., Siddiqui A. 1990. Necator americanus: factors influencing skin penetration by larvae. In: Hookworm disease: current status and new directions (Eds. G. A. Schad and K. S. Warren). Taylor and Francis, London, 329-339.
  • Schad V., Phipps R. P. 1989. Prostaglandin E2-dependent induction of B cell unresponsiveness. Role of surface Ig and Fc receptors. Journal of Immunology, 143, 2127-2132.
  • Stankiewicz M., Cabaj W., Pernthaner A., Hadaś E. 1996. Immunization of sheep by drug-abbreviated infections of Ostertagia circumcincta and Trichostrongylus colubriformis against field challenge of gastro-intestinal nematodes. Veterinary Parasitology, 67, 121-132.
  • Van der Pouw Kraan T. C. T. M., Boeije L. C., Smeenk R. J. T., Wijdens J., Aarden L. A. 1995. Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production. Journal of Experimental Medicine, 181, 775-779.
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Typ dokumentu

Bibliografia

Identyfikatory

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