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Czasopismo

2003 | 62 | 3 |

Tytuł artykułu

Vasoactive intestinal polypeptide [VIP] - immunoreactive nerve fibres in the mammary gland of the pig

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Immunohistochemical studies have been performed to investigate the coexistence of VIP with dopamine-β-hydroxylase (DβH), vesicular acetylcholine transporter (VAChT), somatostatin (SOM) or neuropeptyd Y (NPY) within nerve fibres supplying the immature mammary gland in the pig. Generally, a moderate number of the VIP-immunoreactive (VIP-IR) nerve fibres were located in the nipple and parenchyma of the gland. VIP-IR fibres surrounded smooth muscle cells (SMC), blood vessels (BV) and lactiferous ducts (LD). Double-labelling immunohistochemistry revealed that some of VIP-IR nerve fibres also contained immunoreactivity to DβH. VIP/DβH-IR nerves were associated with BV and SMC and single fibres were observed around the LD in both nipple and parenchyma of the gland. VIP/VAChT-IR nerve fibres were not observed. The majority of VIP-IR fibres associated with SMC were also SOM-IR. Less numerous VIP/SOM-IR fibres supplied the BV and were located around the LD of the gland. A small number of VIP-IR nerves also displayed immunoreactivity to NPY. VIP/NPY-IR nerve fibres supplied the BV of the gland.

Wydawca

-

Czasopismo

Rocznik

Tom

62

Numer

3

Opis fizyczny

p.267-270,fig.,ref.

Twórcy

  • University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10-957 Olsztyn, Poland

Bibliografia

  • 1. Eriksson M, Lind B, Uvnas-Moberg K, Hokfelt T (1996) Distribution and origin of peptide-containing nerve fibres in the rat and human mammary gland. Neuroscience, 70: 227–245.
  • 2. Hil EL, Elde R (1989) Vasoactive intestinal peptide distribution and colocalisation with dopamine-b-hydroxylase in sympathetic chain ganglia of pig. J Auton Nerv Sys, 27: 299–239.
  • 3. Hohmann EL, Elde RP, Rysavy IA, Einzig S, Gebhard RL (1986) Innervation of periosteum and bone sympathetic vasoactive intestinal peptide-containing nerve fibres. Science, 232: 868–871.
  • 4. Franke-Radowiecka A (2002) Distribution and immunohistochemical characterisation of symphatetic chain ganglia (SChG) neurons supplying the porcine mammary gland. Neuropeptides, 36: 485.
  • 5. Said SI, Mutt V (1984) Vasoactive intestinal polypeptide (VIP): current status. Peptides, 5: 143–150.
  • 6. Skakkebćk M, Hannibal J, Fahrenkrug J (1999) Pituitary adenylate cyclase activating polypeptide (PACAP) in the rat mammary gland. Cell Tissue Res, 298: 153–159.
  • 7. Thulesen J, Rasmussen TN, Schmidt P, Holst JJ, Poulsen SS, (1994) Calcitonin gene-related peptide (CGRP) in the nipple of the mammary gland. Histochemistry, 102: 437–444.
  • 8. Uvnäs-Moberg K, Eriksson M (1996) Breastfeeding: physiological, endocrine and behavioural adaptations caused by oxytocin and local neurogenic activity in the nipple and mammary gland. Acta Paediatr, 85: 525–530.
  • 9. Wessendorf MW, Elde RP (1985) Characterisation of an immunofluorescence technique for the demonstration of coexisting neurotransmitters within nerve fibres and terminals. J Histochem Cytochem, 33: 984–994.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-9f343411-4326-4d37-8183-845569e7af9f
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