Molecular basis for the functional diversity of enzyme forms of the LMW [Mr 38000] acid phosphatase of the frog liver

• Autorzy: Kubicz A.
• Języki publikacji: EN

Abstrakty

EN

Recent studies on the structure and function of the tartrate-resistant acid phosphatase (Mr 38 000) of the frog liver arc reviewed. The nature of the enzyme heterogeneity is elucidated on a molecular and physiologi­cal basis. The following structure-activity relationship is proposed: the enzyme protein is modified by glycosylation processes leading to forma­tion of the different enzyme forms. The oligosaccharide chain stabilizes the final structure of the enzyme forms with altered conformation causing different exposure of the essential functional groups (e.g. sulfliydryl residues, antigen determinants). This leads to different physiological events necessary for fulfillment of metabolic requirements of the cell.

Słowa kluczowe

EN

acid phosphatase; enzyme; frog; liver

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 1992
• Tom: 39
• Numer: 2
• Opis fizyczny: p.165-176,fig.

Twórcy

autor

Kubicz A.

• University of Wroclaw, Tamka 2, 50-137 Wroclaw, Poland

Bibliografia

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