Genom psa i jego wykorzystanie w badaniach mikromacierzy u psow

• Autorzy: Zmudzka M , Jank M. , Lechowski R. , Micun J.

Warianty tytułu

EN

Canine genome research using the DNA microarray technique

• Języki publikacji: PL

Abstrakty

EN

The review presents a summary of knowledge on canine genome research using the DNA microarray technique - a new tool in molecular biology. Canine genome was sequenced in 2005, and since then numerous studies on gene expression in various tissues and organs as well as in different physiological or pathological conditions have been published. Canine DNA microarray has been used in research on neoplastic diseases (e.g. brain tumor), kidney diseases (Alport syndrome, hypertension in obese dogs), cardiac diseases (atrial fibrillation, dilation of the heart) and cartilage diseases. This technique has also enabled the analysis of gene expression in acute phase response and in renal tubular epithelial cell line (MDCK) stimulated by hepatocyte growth factor.

Słowa kluczowe

PL

genetyka zwierzat; psy; genomy; mikromacierze DNA; zastosowanie

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2010
• Tom: 66
• Numer: 01
• Opis fizyczny: s.22-26,bibliogr.

Twórcy

autor

Zmudzka M

• Szkola Glowna Gospodarstwa Wiejskiego, ul.Nowoursynowska 159 C, 02-787 Warszawa

autor

Jank M.

autor

Lechowski R.

autor

Micun J.

Bibliografia

• 1.Asakura M., Takashima S., Asano Y., Honma T., Asanuma H., Sanada S., Shintani Y., Liao Y., Kim Y., Ogita H., Node K., Minamino T., Yorikane R., Agai A., Kitamura S., Tomoike H., Hori M., Kitakaze M.: Canine DNA array as a potential Tool for combining physiology and molecular biology. Circ. J. 2003, 67, 788-792.
• 2.Balkovetz D. F., Gerrard E. R., Li S., Johnson D., Lee J., Tobias J. W., Rogers K. K., Snyder R. W., Lipshutz J. H.: Gene expression alterations during HGF-induced dedifferentiation of renal tubular epithelial cell line (MDCK) using a novel canine DNA microarray. Am. J. Physiol. Renal Physiol. 2004, 286, 702-710.
• 3.Burton-Wurster N., Mateescu R. G., Todhunter R. J., Clements K. M., Sun Q., Scarpino V, Lust G.: Genes in Canine Articular Cartilage That Respond to Mechanical Injury: Gene Expression Studies With Affymetrix canine GeneChip. J. Hered. 2005, 96, 821-828.
• 4.Cardin S., Libby E., Pelletier P., Le Bouter S., Shiroshita-Takeshita A., Le Meur N., Leger J., Demolombe S., Ponton A., Glass L., Nattel S.: Contrasting gene expression profiles in two canine models of atrial fibrillation. Circulation Res. 2007, 100, 425-441.
• 5.Enerson B. E., Lin A., Lu B., Zhao H., Lawton M. P., Floyd E.: Acute drug-induced vasxular injury in beagle dogs: pathology and correlating genomic expression. Toxicol.Pathol. 2006, 34, 27-32.
• 6.Euler H. Von, Khoshnoud R., He Q., Khoshnoud A., Fornander T., Rutqvist L. E., Skog S.: Time-dependent RNA degradation affecting cDNA array quality in sponteneus canine tumours sampled using standard surgical procedures. Int. J. Mol. Med. 2005, 16, 979-985.
• 7.Greer K. A., Higgins M. A., Cox M. L., Ryan T. P., Berridge B. R., Kashtan C. E., Lees G. E., Murphy K. E.: Gene expression analysis in canine model of X-linked Alport Syndrome. Mamm. Genome 2006, 17, 976-990.
• 8.Gu J. W., Wang J., Stockton A., Lokitz B., Henegar L., Hall J. E.: Cytokine gene expression profiles in kidney medulla and cortex of obese hypertensive dogs. Kidney Int. 2004, 66, 713-721.
• 9.Higgins M. A., Berridge B. R., Mills B. J., Schultze A. E., Gao H., Searfoss G. H., Baker T. K., Ryan T. P.: Gene expression analysis of the acute phase response using a canine microarray. Toxicol. Sci. 2003, 74, 470-484.
• 10.Król M., Pawłowski K. M., Motyl T.: Mikromacierze DNA w onkologii weterynaryjnej. Medycyna Wet. 2009, 65, 377-380.
• 11.Lee Z., Hever A., Willhite D., Zlotnik A., Hevezi P.: Effects of RNA degradation on gene expression analysis of human postmortem tissues. FASEB J. 2005, 19, 1356-1358.
• 12.Lindblad-Toh K.: Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature 2005, 438, 803-819.
• 13.Merryman-Simpson A. E., Wood S. H., Fretwell N., Jones P. G., McLaren W. M., McEwan N. A., Clements D. N., Carter S. D, Ollier W. E., Nuttal T.: Gene (mRNA) expression in canine atopic dermatitis: microarray analysis. Vet. Dermatol. 2008, 19, 59-66.
• 14.Oyama M. A., Chittur S.: Genomic expression patterns of cardiac tissues from dogs with dilated cardiomyopathy. Am. J. Vet. Res. 2005, 66, 1140-1155.
• 15.Paez G. L., Sellers K. F., Band M., Acland G. M., Zangerl B., Aquirre G. D.: Characterization of gene expression profiles of normal canine retina and brain using a retinal cDNA microarray. Mol. Vision 2006, 12, 1048-1056.
• 16.Rao N. A., van Wolferen M. E., van der Ham R., van Leenen D., Groot Koerkamp M. J., Holstege F. C., Mol J. A.: cDNA microarray profiles of canine mammary tumor cell lines reveal deregulated pathways pertaining to their phenotype. Anim. Genet. 2008, 39, 333-345.
• 17.Sadkowski T., Motyl T.: Mikromacierze DNA - nowe narzędzie badawcze w fizjologii i patologii. Medycyna Wet. 2007, 63, 1421-1426.
• 18.Sakai D., Nakai T., Mochida J., Alini M., Grad S.: Differential phenotype of intervertebral disc cells: microarray and immunohistochemical analysis of canine nucleus pulposus and annulus fibrosus. Spine 2009, 34, 1448-1456.
• 19.Stan A. D., Ghose S., Gao X. M., Roberts R. C., Lewis-Amezcua K., Hatanpaa K. J., Tamminga C. A.: Human postmortem tissue: what quality markers matter?, Brain Res. 2006, 1123, 1-11.
• 20.Thomas R., Fiegler H., Ostrander E. A., Galibert F., Carter N. P., Breen M.: A canine cancer-gene microarray for CGH analysis of tumors. Cyt. Gen. Res. 2003, 102, 254-260.
• 21.Thomson S. A. M., Kennerly E., Olby N., Mickelson J. R., Hoffmann D. E., Dickinson P. J., Gibson G., Breen M.: Microarray analysis of differentially expressed genes of primary tumors in canine central nervous system. Vet. Pathol. 2005, 42, 550-558.
• 22.Zheng J., Chen Y., Pat B., Dell'italia L. A., Tillson M., Dillon A. R., Powell P. C., Shi K., Shan N., Denney T., Husain A., Dell'italia L. J.: Microarray identifies extensive downregulation of noncollagen extracellular matrix and profibrotic growth factor genes in chronic isolated mitral regurgitation in the dog. Circulation 2009, 119, 2086-2095.